RANGAP1 anticorps (N-Term)

N° du produit ABIN2856335

Détail du produit anti-RANGAP1 anticorps

Antigène: RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RANGAP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain

Attributs du produit: Rabbit Polyclonal antibody to RanGAP1 (Ran GTPase activating protein 1)
RanGAP1 antibody [N1], N-term

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human RanGAP1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: A431

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur RANGAP1

Antigène: RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))

Autre désignation: Ran GTPase activating protein 1 (RANGAP1 Produits)

Synonymes: anticorps Fug1, anticorps RANGAP, anticorps SD, anticorps ATRANGAP1, anticorps RAN GTPASE-ACTIVATING PROTEIN 1, anticorps RAN GTPase activating protein 1, anticorps RanGAP1, anticorps fug1, anticorps rangap1b, anticorps rna1p, anticorps C79654, anticorps mKIAA1835, anticorps rangap1, anticorps rangap1a, anticorps Protein rna1, anticorps CG9999, anticorps CT28175, anticorps Dmel\CG9999, anticorps RGP1_DROME, anticorps Ran, anticorps RanGAP, anticorps RanGap, anticorps RanGap1, anticorps Scl, anticorps Sd, anticorps Sd-RanGAP, anticorps Sd-RanGap, anticorps dRanGAP, anticorps ranGAP, anticorps ranGap, anticorps rangap, anticorps zgc:154097, anticorps Ran GTPase activating protein 1, anticorps RAN GTPase activating protein 1, anticorps ran GTPase activating protein 1, anticorps Ran GTPase activating protein 1 S homeolog, anticorps Ran GTPase activating protein 1 L homeolog, anticorps Ran GAP Rna1, anticorps Ran GTPase activating protein, anticorps RAN GTPase activating protein 1a, anticorps RANGAP1, anticorps TERG_02084, anticorps rangap1.S, anticorps Rangap1, anticorps rangap1.L, anticorps rna1, anticorps RanGAP, anticorps rangap1a

Sujet: RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1,000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequence is unrelated to that of GTPase activators for other RAS-related proteins, but is 88 % identical to Fug1, the murine homolog of yeast Rna1p. RanGAP1 and RCC1 control RAN-dependent transport between the nucleus and cytoplasm. RanGAP1 is a key regulator of the RAN GTP/GDP cycle.

Cellular Localization: Cytoplasm , Nucleus membrane, Peripheral membrane protein, Cytoplasmic side , Kinetochore (By similarity)

Poids moléculaire: 64 kDa

ID gène: 5905

UniProt: P46060

Pathways: M Phase, Protein targeting to Nucleus