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IPO7 anticorps (C-Term)

KO Validated IPO7 Reactivité: Humain WB, IHC (p), IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2856366
  • Antigène Voir toutes IPO7 Anticorps
    IPO7 (Importin 7 (IPO7))
    Épitope
    • 15
    • 8
    • 7
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 49
    • 21
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 47
    • 1
    • 1
    Lapin
    Clonalité
    • 48
    • 1
    Polyclonal
    Conjugué
    • 18
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IPO7 est non-conjugé
    Application
    • 41
    • 19
    • 19
    • 13
    • 13
    • 8
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    Knockdown/Knockout validation was supported by references (PMID:25999477)
     Réactivité croisée
    Humain
    Attributs du produit
    Rabbit Polyclonal antibody to Importin 7 (importin 7)
    Importin 7 antibody [C3], C-term
    Purification
    Purified by antigen-affinity chromatography.
    Classe de qualité
    KO Validated
    Immunogène
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Importin 7. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product IPO7 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Positive Control: Jurkat

    Validation: KO/KD

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Agent conservateur
    Thimerosal (Merthiolate)
    Précaution d'utilisation
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    IPO7 (Importin 7 (IPO7))
    Autre désignation
    importin 7 (IPO7 Produits)
    Synonymes
    anticorps fb33d09, anticorps wu:fb33d09, anticorps zgc:66425, anticorps zgc:76878, anticorps imp7, anticorps ranbp7, anticorps Imp7, anticorps RANBP7, anticorps A330055O14Rik, anticorps C330016G14, anticorps Ranbp7, anticorps importin 7, anticorps importin 7 S homeolog, anticorps importin-7, anticorps karyopherin, anticorps ipo7, anticorps ipo7.S, anticorps IPO7, anticorps CpipJ_CPIJ002096, anticorps PTRG_08544, anticorps SJAG_03693, anticorps NAEGRDRAFT_71372, anticorps VDBG_01971, anticorps MGYG_08162, anticorps Tsp_01943, anticorps Tsp_01946, anticorps Ipo7
    Sujet
    The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins.

    Cellular Localization: Cytoplasm , Nucleus
    Poids moléculaire
    120 kDa
    ID gène
    10527
    UniProt
    O95373
    Pathways
    Protein targeting to Nucleus
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