IL1RN anticorps
-
- Antigène Voir toutes IL1RN Anticorps
- IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp IL1RN est non-conjugé
-
Application
- Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Réactivité croisée
- Humain, Souris, Rat
- Attributs du produit
-
Rabbit Polyclonal antibody to IL1 Receptor antagonist (interleukin 1 receptor antagonist)
IL1 Receptor antagonist antibody - Purification
- Purified by antigen-affinity chromatography.
- Immunogène
- Recombinant protein encompassing a sequence within the center region of human IL1 Receptor antagonist. The exact sequence is proprietary.
- Isotype
- IgG
-
-
- Indications d'application
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Commentaires
-
Positive Control: Neuro2A whole , C8D30 , NIH-3T3 , Raw264.7 , C2C12 , PC-12
Validation: Orthogonal
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.86 mg/mL
- Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
Autoantibodies against interleukin-1 receptor antagonist in multisystem inflammatory syndrome in children: a multicentre, retrospective, cohort study. ..." dans: The Lancet. Rheumatology, Vol. 4, Issue 5, pp. e329-e337, (2022) (PubMed).
: "
-
Autoantibodies against interleukin-1 receptor antagonist in multisystem inflammatory syndrome in children: a multicentre, retrospective, cohort study. ..." dans: The Lancet. Rheumatology, Vol. 4, Issue 5, pp. e329-e337, (2022) (PubMed).
-
- Antigène
- IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))
- Autre désignation
- interleukin 1 receptor antagonist (IL1RN Produits)
- Synonymes
- anticorps DIRA, anticorps ICIL-1RA, anticorps IL-1RN, anticorps IL-1ra, anticorps IL-1ra3, anticorps IL1F3, anticorps IL1RA, anticorps IRAP, anticorps MVCD4, anticorps IRAP1, anticorps IL1RN, anticorps IL-1RA, anticorps F630041P17Rik, anticorps interleukin 1 receptor antagonist, anticorps interleukin 1 receptor antagonist-like, anticorps IL1RN, anticorps Il1rn, anticorps IL1RNL
- Sujet
-
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
Cellular Localization: Isoform 1: Secreted , Isoform 2: Cytoplasm , Isoform 3: Cytoplasm , Isoform 4: Cytoplasm - Poids moléculaire
- 20 kDa
- ID gène
- 3557
- UniProt
- P18510
- Pathways
- Signalisation NF-kappaB, Hormone Transport, Cancer Immune Checkpoints
-