SKP1 anticorps

N° du produit ABIN2856416

Détail du produit anti-SKP1 anticorps

Antigène: SKP1 (S-Phase Kinase-Associated Protein 1 (SKP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SKP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris

Attributs du produit: Rabbit Polyclonal antibody to SKP1 (S-phase kinase-associated protein 1)
SKP1 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human SKP1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: NIH-3T3 , A549 , H1299 , HCT116 , MCF-7

Validation: Overexpression

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur SKP1

Antigène: SKP1 (S-Phase Kinase-Associated Protein 1 (SKP1))

Autre désignation: S-phase kinase associated protein 1 (SKP1 Produits)

Synonymes: anticorps EMC19, anticorps OCP-II, anticorps OCP2, anticorps SKP1A, anticorps TCEB1L, anticorps p19A, anticorps 15kDa, anticorps 2610043E24Rik, anticorps 2610206H23Rik, anticorps SKP1, anticorps Tceb1l, anticorps p19Skp1, anticorps Skp1a, anticorps skp1a, anticorps zgc:73186, anticorps ocp2, anticorps emc19, anticorps ocp-ii, anticorps tceb1l, anticorps ARABIDOPSIS SKP1 HOMOLOGUE 1, anticorps ASK1, anticorps ATSKP1, anticorps S phase kinase-associated protein 1, anticorps T4O12.17, anticorps T4O12_17, anticorps UFO INTERACTING PROTEIN 1, anticorps UIP1, anticorps ocp-2, anticorps S-phase kinase associated protein 1, anticorps S-phase kinase-associated protein 1, anticorps S-phase kinase-associated protein 1 pseudogene, anticorps S-phase kinase-associated protein 1A, anticorps S-phase kinase-associated protein 1 S homeolog, anticorps S phase kinase-associated protein 1, anticorps SKP1, anticorps skp1, anticorps LOC100340043, anticorps Skp1a, anticorps Skp1, anticorps skp1.S

Sujet: This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.

Poids moléculaire: 19 kDa

ID gène: 6500

UniProt: P63208

Pathways: Cycle Cellulaire, Signalisation Hedgehog, Mitotic G1-G1/S Phases