DENND1B anticorps (Center)

N° du produit ABIN2856495

Détail du produit anti-DENND1B anticorps

Antigène: DENND1B (DENN/MADD Domain Containing 1B (DENND1B))

Épitope: Center

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DENND1B est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Attributs du produit: Rabbit Polyclonal antibody to DENND1B (DENN/MADD domain containing 1B)
DENND1B antibody [N1C1]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human DENND1B. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*

Commentaires:

Positive Control: 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , mouse brain

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.9 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur DENND1B

Antigène: DENND1B (DENN/MADD Domain Containing 1B (DENND1B))

Autre désignation: DENND1B (DENND1B Produits)

Synonymes: anticorps C1ORF18, anticorps C1orf218, anticorps FAM31B, anticorps 4632404N19Rik, anticorps 4930467M19Rik, anticorps 6820401H01Rik, anticorps F730008N07Rik, anticorps Fam31b, anticorps si:ch211-195i21.1, anticorps DENN domain containing 1B, anticorps DENN/MADD domain containing 1B, anticorps DENND1B, anticorps dennd1b, anticorps Dennd1b

Sujet: Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2, see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).[supplied by OMIM]

Poids moléculaire: 48 kDa

ID gène: 163486