Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

Nemo-Like Kinase anticorps

NLK Reactivité: Humain WB, IF, IHC (p), ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2856544
  • Antigène Voir toutes Nemo-Like Kinase (NLK) Anticorps
    Nemo-Like Kinase (NLK)
    Reactivité
    • 81
    • 35
    • 12
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 82
    • 4
    Lapin
    Clonalité
    • 83
    • 3
    Polyclonal
    Conjugué
    • 26
    • 8
    • 7
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Nemo-Like Kinase est non-conjugé
    Application
    • 78
    • 41
    • 26
    • 26
    • 24
    • 15
    • 13
    • 10
    • 9
    • 6
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
     Réactivité croisée
    Humain, Souris
    Attributs du produit
    Rabbit Polyclonal antibody to NLK (nemo-like kinase)
    NLK antibody [N3C3]
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Recombinant protein encompassing a sequence within the center region of human NLK. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product NLK Anticorps primaire
  • Indications d'application
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Positive Control: Mouse brain , HeLa , NLK-transfected 293T

    Validation: Overexpression

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Agent conservateur
    Thimerosal (Merthiolate)
    Précaution d'utilisation
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    Nemo-Like Kinase (NLK)
    Autre désignation
    nemo like kinase (NLK Produits)
    Synonymes
    anticorps Amf, anticorps Gpi1, anticorps AI194375, anticorps nlk, anticorps nlkb, anticorps zgc:111875, anticorps Xnlk, anticorps nlk1, anticorps nlk2, anticorps NLK, anticorps nemo-like, anticorps RGD1561602, anticorps glucose-6-phosphate isomerase, anticorps nemo like kinase, anticorps nemo-like kinase, type 1, anticorps nemo-like kinase L homeolog, anticorps Nemo-Like kinase, anticorps nemo-like kinase, anticorps Gpi, anticorps NLK, anticorps Nlk, anticorps nlk1, anticorps nlk.L, anticorps nlk, anticorps nemo-like
    Sujet
    Role in cell fate determination, required for differentiation of bone marrow stromal cells. Acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta-catenin signaling pathway and the phosphorylation and destruction of the MYB transcription factor. May suppress a wide range of transcription factors by phosphorylation of the coactivator, CREBBP (By similarity). Involved in TGFbeta-mediated mesoderm induction, acting downstream of MAP3K7/TAK1 to phosphorylate STAT3.

    Cellular Localization: Nucleus (By similarity) , Cytoplasm (By similarity)
    Poids moléculaire
    58 kDa
    ID gène
    51701
    UniProt
    Q9UBE8
    Pathways
    Ubiquitin Proteasome Pathway
Vous êtes ici:
Support technique