INHBA anticorps (C-Term)
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- Antigène Voir toutes INHBA Anticorps
- INHBA (Inhibin, beta A (INHBA))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp INHBA est non-conjugé
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Application
- Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Réactivité croisée
- Humain
- Attributs du produit
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Rabbit Polyclonal antibody to Inhibin beta A (inhibin, beta A)
Inhibin beta A antibody - Purification
- Purified by antigen-affinity chromatography.
- Classe de qualité
- KO Validated
- Immunogène
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Inhibin beta A. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product INHBA Anticorps primaire
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- Indications d'application
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Commentaires
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Validation: KO/KD
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.66 mg/mL
- Buffer
- 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Antigène
- INHBA (Inhibin, beta A (INHBA))
- Autre désignation
- inhibin subunit beta A (INHBA Produits)
- Synonymes
- anticorps EDF, anticorps FRP, anticorps actba, anticorps inhba, anticorps inhbaa-001, anticorps edf, anticorps frp, anticorps INHB, anticorps inhbal, anticorps zgc:158348, anticorps inhibin beta A subunit, anticorps inhibin beta-A, anticorps inhibin, beta Aa, anticorps inhibin beta A, anticorps inhibin, beta Ab, anticorps INHBA, anticorps Inhba, anticorps inhbaa, anticorps inhba, anticorps inhbab
- Sujet
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The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.
Cellular Localization: Secreted - Poids moléculaire
- 47 kDa
- ID gène
- 3624
- UniProt
- P08476
- Pathways
- Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Autophagy
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