CD70 anticorps (C-Term)

N° du produit ABIN2856605

Détail du produit anti-CD70 anticorps

Antigène: CD70 (CD70 Molecule (CD70))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD70 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Humain

Attributs du produit: Rabbit polyclonal antibody to CD27L (CD27L (CD70)) (CD27L (CD70) molecule)
CD70 antibody [C2C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CD70. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: Jurkat

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur CD70

Antigène: CD70 (CD70 Molecule (CD70))

Autre désignation: CD70 molecule (CD70 Produits)

Synonymes: anticorps CD27LG, anticorps Cd27l, anticorps Tnfsf7, anticorps CD27L, anticorps TNFSF7, anticorps CD70 antigen, anticorps CD70 molecule, anticorps Cd70 molecule, anticorps Cd70, anticorps CD70

Sujet: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.

Cellular Localization: Membrane

Poids moléculaire: 21 kDa

ID gène: 970

UniProt: P32970

Pathways: Cancer Immune Checkpoints