IL-24 anticorps (C-Term)

N° du produit ABIN2856609

Détail du produit anti-IL-24 anticorps

Antigène: IL-24 (IL24) (Interleukin 24 (IL24))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-24 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain

Attributs du produit: Rabbit polyclonal antibody to Interleukin-24 (interleukin 24)
Interleukin-24 antibody [C2C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human IL24. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: A431

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.46 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur IL-24

Antigène: IL-24 (IL24) (Interleukin 24 (IL24))

Autre désignation: interleukin 24 (IL24 Produits)

Synonymes: anticorps C49A, anticorps FISP, anticorps IL10B, anticorps MDA7, anticorps MOB5, anticorps ST16, anticorps Mda7, anticorps St16, anticorps Mda-7, anticorps IL24, anticorps interleukin 24, anticorps IL24, anticorps Il24

Sujet: This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27 kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Cellular Localization: Secreted

Poids moléculaire: 24 kDa

ID gène: 11009

UniProt: Q13007

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Autophagy