LITAF anticorps

N° du produit ABIN2856656

Détail du produit anti-LITAF anticorps

Antigène: LITAF (Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LITAF est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ChIP DNA-Sequencing (ChIP-seq)

Réactivité croisée: Humain

Attributs du produit: Rabbit polyclonal antibody to LITAF (lipopolysaccharide-induced TNF factor)
LITAF antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human LITAF. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: HepG2

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur LITAF

Antigène: LITAF (Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))

Autre désignation: lipopolysaccharide induced TNF factor (LITAF Produits)

Synonymes: anticorps PIG7, anticorps SIMPLE, anticorps TP53I7, anticorps EET-1, anticorps Pig7, anticorps TNF-alpha, anticorps 3222402J11Rik, anticorps C85531, anticorps N4WBP3, anticorps TBX1, anticorps lipopolysaccharide induced TNF factor, anticorps lipopolysaccharide-induced TNF factor, anticorps LPS-induced TN factor, anticorps LITAF, anticorps Litaf

Sujet: Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene.

Cellular Localization: Lysosome membrane, Peripheral membrane protein, Cytoplasmic side

Poids moléculaire: 17 kDa

ID gène: 9516

UniProt: Q99732

Pathways: Cellular Response to Molecule of Bacterial Origin