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DNASE1 anticorps

DNASE1 Reactivité: Humain WB, ICC, IF, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2856669
  • Antigène Voir toutes DNASE1 Anticorps
    DNASE1 (Deoxyribonuclease I (DNASE1))
    Reactivité
    • 60
    • 26
    • 14
    • 14
    Humain
    Hôte
    • 59
    • 12
    • 1
    Lapin
    Clonalité
    • 62
    • 10
    Polyclonal
    Conjugué
    • 35
    • 10
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DNASE1 est non-conjugé
    Application
    • 59
    • 23
    • 17
    • 13
    • 13
    • 10
    • 9
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain, Singe
    Attributs du produit
    Rabbit Polyclonal antibody to DNase I (deoxyribonuclease I)
    DNase I antibody [N1C3]
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Recombinant protein corresponding to human DNase I.
    Isotype
    IgG
    Top Product
    Discover our top product DNASE1 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.19 mg/mL
    Buffer
    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    DNASE1 (Deoxyribonuclease I (DNASE1))
    Autre désignation
    deoxyribonuclease 1 (DNASE1 Produits)
    Synonymes
    anticorps LOC397802, anticorps DNL1, anticorps DRNI, anticorps AI788650, anticorps DNaseI, anticorps Dnl1, anticorps dnase1-A, anticorps zgc:92440, anticorps DNase I, anticorps deoxyribonuclease 1, anticorps deoxyribonuclease I, anticorps deoxyribonuclease I L homeolog, anticorps Deoxyribonuclease I, anticorps endA, anticorps LOC397802, anticorps DNASE1, anticorps Dnase1, anticorps dnase1.L, anticorps dnase1, anticorps CpipJ_CPIJ011184, anticorps CpipJ_CPIJ011185, anticorps CpipJ_CPIJ011186, anticorps CpipJ_CPIJ011187, anticorps CpipJ_CPIJ011190, anticorps CpipJ_CPIJ017803, anticorps Desal_1409, anticorps MPET_RS05255, anticorps METEV_RS02275, anticorps Plabr_0631
    Sujet
    This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

    Cellular Localization: Secreted , Nucleus envelope
    Poids moléculaire
    31 kDa
    ID gène
    1773
    UniProt
    P24855
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