PSMC3 anticorps

N° du produit ABIN2856692

Détail du produit anti-PSMC3 anticorps

Antigène: PSMC3 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 (PSMC3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMC3 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Whole Mount) (IHC (wm))

Réactivité croisée: Humain, Poisson zèbre (Danio rerio)

Attributs du produit: Rabbit polyclonal antibody to PSMC3 (proteasome (prosome, macropain) 26S subunit, ATPase, 3)
PSMC3 antibody [N1C2]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human PSMC3. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: Molt-4

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur PSMC3

Antigène: PSMC3 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 (PSMC3))

Autre désignation: proteasome 26S subunit, ATPase 3 (PSMC3 Produits)

Synonymes: anticorps TBP1, anticorps TBP-1, anticorps wu:fb39a02, anticorps zgc:86713, anticorps psmc3, anticorps MGC89608, anticorps PSMC3, anticorps NV15940, anticorps 23.m06430, anticorps DDBDRAFT_0186002, anticorps DDBDRAFT_0232967, anticorps DDB_0186002, anticorps DDB_0232967, anticorps psmc3-b, anticorps tbp10, anticorps psmc3-a, anticorps proteasome 26S subunit, ATPase 3, anticorps proteasome (prosome, macropain) 26S subunit, ATPase 3, anticorps 26S protease regulatory subunit 6A, anticorps 26S protease regulatory subunit 6a, anticorps 26S protease regulatory subunit 6A-B, anticorps 26S protease regulatory subunit 6A, putative, anticorps proteasome 26S subunit, ATPase 3 S homeolog, anticorps nth-like DNA glycosylase 1 S homeolog, anticorps PSMC3, anticorps Psmc3, anticorps HCAG_00069, anticorps GL50803_4365, anticorps EDI_316920, anticorps CpipJ_CPIJ006888, anticorps CpipJ_CPIJ006889, anticorps CpipJ_CPIJ010864, anticorps prs6a, anticorps psmc3, anticorps LOC100115023, anticorps BBOV_IV004580, anticorps CGB_M2140W, anticorps psmC3, anticorps LOC100637883, anticorps psmc3.S, anticorps nthl1.S

Sujet: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9.

Cellular Localization: Cytoplasm (Potential) , Nucleus

Poids moléculaire: 49 kDa

ID gène: 5702

UniProt: P17980

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway