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FGD4 anticorps

FGD4 Reactivité: Humain WB, ICC, IHC (p), IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2856709
  • Antigène Voir toutes FGD4 Anticorps
    FGD4 (FYVE, RhoGEF and PH Domain Containing 4 (FGD4))
    Reactivité
    • 22
    • 1
    • 1
    Humain
    Hôte
    • 22
    Lapin
    Clonalité
    • 22
    Polyclonal
    Conjugué
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp FGD4 est non-conjugé
    Application
    • 21
    • 13
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
     Réactivité croisée
    Humain
    Attributs du produit
    Rabbit polyclonal antibody to FGD4 (FYVE, RhoGEF and PH domain containing 4)
    FGD4 antibody [N1N3]
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Recombinant protein encompassing a sequence within the center region of human FGD4. The exact sequence is proprietary.
    Isotype
    IgG
  • Indications d'application
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Positive Control: Molt-4

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Agent conservateur
    Thimerosal (Merthiolate)
    Précaution d'utilisation
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    FGD4 (FYVE, RhoGEF and PH Domain Containing 4 (FGD4))
    Autre désignation
    FYVE, RhoGEF and PH domain containing 4 (FGD4 Produits)
    Synonymes
    anticorps CMT4H, anticorps FRABP, anticorps ZFYVE6, anticorps 9030023J02Rik, anticorps 9330209B17Rik, anticorps Frabp, anticorps FYVE, RhoGEF and PH domain containing 4, anticorps FGD4, anticorps Fgd4
    Sujet
    This gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape. This protein contains an actin filament-binding domain, which together with its Dbl homology domain and one of its pleckstrin homology domains, can form microspikes. This protein can activate MAPK8 independently of the actin filament-binding domain, and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP. The activation of CDC42 also enables this protein to play a role in mediating the cellular invasion of Cryptosporidium parvum, an intracellular parasite that infects the gastrointestinal tract. Mutations in this gene can cause Charcot-Marie-Tooth disease type 4H (CMT4H), a disorder of the peripheral nervous system.

    Cellular Localization: Cytoplasm , cytoskeleton (By similarity) , Cell projection , filopodium (By similarity)
    Poids moléculaire
    87 kDa
    ID gène
    121512
    UniProt
    Q96M96
    Pathways
    Neurotrophin Signaling Pathway
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