Lamin B2 anticorps
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- Antigène Voir toutes Lamin B2 (LMNB2) Anticorps
- Lamin B2 (LMNB2)
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Lamin B2 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
- Réactivité croisée
- Humain, Souris
- Attributs du produit
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Rabbit Polyclonal antibody to Lamin B2 (lamin B2)
Lamin B2 antibody [N3C2], Internal - Purification
- Purified by antigen-affinity chromatography.
- Immunogène
- Recombinant protein encompassing a sequence within the center region of human Lamin B2. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product LMNB2 Anticorps primaire
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- Indications d'application
- WB: 1:500-1:40000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Commentaires
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Positive Control: Neuro2A , GL261 , C8D30 , NIH-3T3 , BCL-1 , Raw264.7 , C2C12
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.73 mg/mL
- Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Antigène
- Lamin B2 (LMNB2)
- Autre désignation
- lamin B2 (LMNB2 Produits)
- Sujet
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The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B2. This gene is in a head-to-tail orientation with the gene for the translocase of inner mitochondrial membrane 13 homolog gene.
Cellular Localization: Nucleus inner membrane, Lipid-anchor, Nucleoplasmic side - Poids moléculaire
- 68 kDa
- ID gène
- 84823
- UniProt
- Q03252
- Pathways
- Apoptose, Caspase Cascade in Apoptosis
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