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FIG4 anticorps (Center)

FIG4 Reactivité: Humain WB, IHC (p), ICC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2856730
  • Antigène Voir toutes FIG4 Anticorps
    FIG4 (FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4))
    Épitope
    • 15
    • 8
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    Center
    Reactivité
    • 28
    • 16
    • 15
    • 1
    Humain
    Hôte
    • 43
    • 1
    Lapin
    Clonalité
    • 43
    • 1
    Polyclonal
    Conjugué
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FIG4 est non-conjugé
    Application
    • 36
    • 17
    • 13
    • 13
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)
     Réactivité croisée
    Chimpanzé
    Réactivité croisée (Details)
    Chimpanzee (100 %)
    Attributs du produit
    Rabbit Polyclonal antibody to FIG4 (FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae))
    FIG4 antibody
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Recombinant protein encompassing a sequence within the center region of human FIG4. The exact sequence is proprietary.
    Isotype
    IgG
  • Indications d'application
    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
    Commentaires

    Positive Control: HeLa , HCT116

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Agent conservateur
    Thimerosal (Merthiolate)
    Précaution d'utilisation
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    FIG4 (FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4))
    Autre désignation
    FIG4 (FIG4 Produits)
    Synonymes
    anticorps A530089I17Rik, anticorps AI326867, anticorps Sac3, anticorps ALS11, anticorps CMT4J, anticorps KIAA0274, anticorps SAC3, anticorps YVS, anticorps dJ249I4.1, anticorps Kiaa0274, anticorps RGD1311375, anticorps FIG4 phosphoinositide 5-phosphatase, anticorps Fig4, anticorps FIG4
    Sujet
    The protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J.

    Cellular Localization: Endosome membrane
    Poids moléculaire
    104 kDa
    ID gène
    9896
    Pathways
    Inositol Metabolic Process
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