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GALNS anticorps (Center)

GALNS Reactivité: Humain, Souris, Rat WB, IF, IHC (p), ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2856743
  • Antigène Voir toutes GALNS Anticorps
    GALNS (Galactosamine (N-Acetyl)-6-Sulfate Sulfatase (GALNS))
    Épitope
    • 15
    • 7
    • 7
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 54
    • 2
    • 1
    Lapin
    Clonalité
    • 57
    Polyclonal
    Conjugué
    • 21
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GALNS est non-conjugé
    Application
    • 43
    • 25
    • 19
    • 15
    • 13
    • 13
    • 13
    • 9
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Attributs du produit
    Rabbit Polyclonal antibody to GALNS (galactosamine (N-acetyl)-6-sulfate sulfatase)
    GALNS antibody
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Recombinant protein encompassing a sequence within the center region of human GALNS. The exact sequence is proprietary.
    Isotype
    IgG
  • Indications d'application
    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
    Commentaires

    Positive Control: H1299 , Neuro2A , C2C12 , PC-12 , Rat2

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Agent conservateur
    Thimerosal (Merthiolate)
    Précaution d'utilisation
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    GALNS (Galactosamine (N-Acetyl)-6-Sulfate Sulfatase (GALNS))
    Autre désignation
    GALNS (GALNS Produits)
    Synonymes
    anticorps GALNAC6S, anticorps GAS, anticorps GalN6S, anticorps MPS4A, anticorps mFLJ00319, anticorps galns, anticorps zgc:158385, anticorps galactosamine (N-acetyl)-6-sulfatase, anticorps galactosamine (N-acetyl)-6-sulfate sulfatase, anticorps N-acetylgalactosamine-6-sulfatase, anticorps galactosamine (N-acetyl)-6-sulfatase L homeolog, anticorps GALNS, anticorps Galns, anticorps Celly_0425, anticorps galns.L, anticorps galns
    Sujet
    This gene encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate. Sequence alterations including point, missense and nonsense mutations, as well as those that affect splicing, result in a deficiency of this enzyme. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder.

    Cellular Localization: Lysosome
    Poids moléculaire
    58 kDa
    ID gène
    2588
    Pathways
    Glycosaminoglycan Metabolic Process
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