SENP2 anticorps (N-Term)

N° du produit ABIN2856760

Détail du produit anti-SENP2 anticorps

Antigène: SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SENP2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)

Réactivité croisée: Boeuf (Vache)

Réactivité croisée (Details): Bovine (88 %)

Attributs du produit: Rabbit Polyclonal antibody to SENP2 (sentrin-specific protease 2)
SENP2 antibody [N1], N-term

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human SENP2. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Commentaires:

Positive Control: 293T , Molt-4

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-SENP2 (ABIN2856760)

Zhou, Zheng, Hu, Wang, Zhang, Zou, Zhong, Wang, Wu, Kang: "SUMOylation stabilizes hSSB1 and enhances the recruitment of NBS1 to DNA damage sites." dans: Signal transduction and targeted therapy, Vol. 5, Issue 1, pp. 80, (2020) (PubMed).

Détails sur SENP2

Antigène: SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))

Autre désignation: SENP2 (SENP2 Produits)

Synonymes: anticorps 2310007L05Rik, anticorps 4930538C18Rik, anticorps AI646780, anticorps AW554757, anticorps Smt3ip2, anticorps SuPr-1, anticorps mKIAA1331, anticorps AXAM2, anticorps SMT3IP2, anticorps Axam, anticorps SUMO/sentrin specific peptidase 2, anticorps SUMO1/sentrin/SMT3 specific peptidase 2, anticorps Sumo1/sentrin/SMT3 specific peptidase 2, anticorps Senp2, anticorps SENP2

Sujet: SUMO1 (UBL1, MIM 601912) is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1 into the conjugatable form and catalyze the deconjugation of SUMO1-containing species.[supplied by OMIM]

Cellular Localization: Nucleus , nuclear pore complex , Nucleus membrane, Peripheral membrane protein, Nucleoplasmic side , Cytoplasm

Poids moléculaire: 68 kDa

ID gène: 59343

Pathways: Chromatin Binding