ZC3H12A anticorps
-
- Antigène Voir toutes ZC3H12A Anticorps
- ZC3H12A (Zinc Finger CCCH-Type Containing 12A (ZC3H12A))
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp ZC3H12A est non-conjugé
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificité
- Knockdown/Knockout validation was supported by references (PMID:27322373)
- Réactivité croisée
- Humain
- Attributs du produit
-
Rabbit Polyclonal antibody to ZC3H12A (zinc finger CCCH-type containing 12A)
ZC3H12A antibody [N3C3] - Purification
- Purified by antigen-affinity chromatography.
- Classe de qualité
- KO Validated
- Immunogène
- Recombinant protein encompassing a sequence within the center region of human ZC3H12A. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product ZC3H12A Anticorps primaire
-
-
- Indications d'application
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Commentaires
-
Validatio: KO/KD, Orthogonal
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1.8 mg/mL
- Buffer
- 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
Pharmacological inhibition of MALT1 protease activity suppresses endothelial activation via enhancing MCPIP1 expression." dans: Cellular signalling, Vol. 50, pp. 1-8, (2019) (PubMed).
: "Central role of myeloid MCPIP1 in protecting against LPS-induced inflammation and lung injury." dans: Signal transduction and targeted therapy, Vol. 2, pp. 17066, (2017) (PubMed).
: "MCPIP1 contributes to the toxicity of proteasome inhibitor MG-132 in HeLa cells by the inhibition of NF-κB." dans: Molecular and cellular biochemistry, Vol. 395, Issue 1-2, pp. 253-63, (2015) (PubMed).
: "Proteasome inhibitor MG-132 induces MCPIP1 expression." dans: The FEBS journal, Vol. 280, Issue 11, pp. 2665-74, (2013) (PubMed).
: "MCP-induced protein 1 suppresses TNFalpha-induced VCAM-1 expression in human endothelial cells." dans: FEBS letters, Vol. 584, Issue 14, pp. 3065-72, (2010) (PubMed).
: "
-
Pharmacological inhibition of MALT1 protease activity suppresses endothelial activation via enhancing MCPIP1 expression." dans: Cellular signalling, Vol. 50, pp. 1-8, (2019) (PubMed).
-
- Antigène
- ZC3H12A (Zinc Finger CCCH-Type Containing 12A (ZC3H12A))
- Autre désignation
- zinc finger CCCH-type containing 12A (ZC3H12A Produits)
- Synonymes
- anticorps CGA, anticorps MCPIP, anticorps MCPIP1, anticorps RP3-423B22.1, anticorps dJ423B22.1, anticorps BC036563, anticorps Mcpip1, anticorps RGD1306776, anticorps chromogranin A, anticorps zinc finger CCCH-type containing 12A, anticorps zinc finger CCCH type containing 12A, anticorps CHGA, anticorps ZC3H12A, anticorps Zc3h12a
- Sujet
-
ZC3H12A is an MCP1 (CCL2, MIM 158105)-induced protein that acts as a transcriptional activator and causes cell death of cardiomyocytes, possibly via induction of genes associated with apoptosis.[supplied by OMIM]
Cellular Localization: Cytoplasm (By similarity) , Nucleus - Poids moléculaire
- 66 kDa
- ID gène
- 80149
- UniProt
- Q5D1E8
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of fat Cell Differentiation
-