Fission 1 anticorps (full length)
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- Antigène Voir toutes Fission 1 (FIS1) Anticorps
- Fission 1 (FIS1)
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Épitope
- full length
- Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Fission 1 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Réactivité croisée
- Macaque rhésus
- Réactivité croisée (Details)
- Rhesus Monkey (100 %)
- Attributs du produit
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Rabbit Polyclonal antibody to FIS1 (fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae))
FIS1 antibody - Purification
- Purified by antigen-affinity chromatography.
- Immunogène
- Full length human FIS1 Recombinant protein.
- Isotype
- IgG
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- Indications d'application
- Suggested dilution Reference ICC/IF 1:100-1:2000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:20000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:2000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:20000*
- Commentaires
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Positive Control: Raji , 293T , A431 , HeLa , HepG2 , mouse liver , mouse brain , rat brain
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- Agent conservateur
- Thimerosal (Merthiolate)
- Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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Brain Overexpression of Uncoupling Protein-2 (UCP2) Delays Renal Damage and Stroke Occurrence in Stroke-Prone Spontaneously Hypertensive Rats." dans: International journal of molecular sciences, Vol. 21, Issue 12, (2020) (PubMed).
: "Silver Nanoparticle Exposure Causes Pulmonary Structural Damage and Mitochondrial Dynamic Imbalance in the Rat: Protective Effects of Sodium Selenite." dans: International journal of nanomedicine, Vol. 15, pp. 633-645, (2020) (PubMed).
: "Empagliflozin Protects HK-2 Cells from High Glucose-Mediated Injuries via a Mitochondrial Mechanism." dans: Cells, Vol. 8, Issue 9, (2020) (PubMed).
: "STX17 dynamically regulated by Fis1 induces mitophagy via hierarchical macroautophagic mechanism." dans: Nature communications, Vol. 10, Issue 1, pp. 2059, (2019) (PubMed).
: "The impact of exercise on mitochondrial dynamics and the role of Drp1 in exercise performance and training adaptations in skeletal muscle." dans: Molecular metabolism, Vol. 21, pp. 51-67, (2019) (PubMed).
: "Irisin alleviates liver ischemia-reperfusion injury by inhibiting excessive mitochondrial fission, promoting mitochondrial biogenesis and decreasing oxidative stress." dans: Redox biology, Vol. 20, pp. 296-306, (2019) (PubMed).
: "Empagliflozin normalizes the size and number of mitochondria and prevents reduction in mitochondrial size after myocardial infarction in diabetic hearts." dans: Physiological reports, Vol. 6, Issue 12, pp. e13741, (2019) (PubMed).
: "Mitochondrial Dynamics in Rat Heart Induced by 5-Fluorouracil." dans: Medical science monitor : international medical journal of experimental and clinical research, Vol. 24, pp. 6666-6672, (2018) (PubMed).
: "Metabolic Stress-Induced Phosphorylation of KAP1 Ser473 Blocks Mitochondrial Fusion in Breast Cancer Cells." dans: Cancer research, Vol. 76, Issue 17, pp. 5006-18, (2017) (PubMed).
: "Mitochondrial Dysregulation Secondary to Endoplasmic Reticulum Stress in Autosomal Dominant Tubulointerstitial Kidney Disease - UMOD (ADTKD-UMOD)." dans: Scientific reports, Vol. 7, pp. 42970, (2017) (PubMed).
: "Dengue Virus Impairs Mitochondrial Fusion by Cleaving Mitofusins." dans: PLoS pathogens, Vol. 11, Issue 12, pp. e1005350, (2015) (PubMed).
: "Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilization." dans: Journal of lipid research, Vol. 53, Issue 12, pp. 2610-9, (2012) (PubMed).
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Brain Overexpression of Uncoupling Protein-2 (UCP2) Delays Renal Damage and Stroke Occurrence in Stroke-Prone Spontaneously Hypertensive Rats." dans: International journal of molecular sciences, Vol. 21, Issue 12, (2020) (PubMed).
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- Antigène
- Fission 1 (FIS1)
- Autre désignation
- FIS1 (FIS1 Produits)
- Synonymes
- anticorps TTC11, anticorps 2010003O14Rik, anticorps Ttc11, anticorps fission, mitochondrial 1, anticorps FIS1, anticorps Fis1
- Sujet
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The balance between fission and fusion regulates the morphology of mitochondria. TTC11 is a component of a mitochondrial complex that promotes mitochondrial fission (James et al., 2003 [PubMed 12783892]).[supplied by OMIM]
Cellular Localization: Mitochondrion outer membrane, Single-pass membrane protein , Peroxisome membrane, Single-pass membrane protein - Poids moléculaire
- 17 kDa
- ID gène
- 51024
- Pathways
- Positive Regulation of Endopeptidase Activity
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