HSP70 1A anticorps (Center)

N° du produit ABIN2856787

Détail du produit anti-HSP70 1A anticorps

Antigène: HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))

Épitope: Center

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSP70 1A est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Mouton, Boeuf (Vache)

Réactivité croisée (Details): Sheep (100 %), Bovine (100 %)

Attributs du produit: Rabbit Polyclonal antibody to HSP70 1A (heat shock 70 kDa protein 1A)
HSP70 1A antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human HSP70 1A. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation 1:500-1:1000* Western blot 1:5000-1:20000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Immunoprecipitation1:500-1:1000* Western blot1:5000-1:20000*

Commentaires:

Positive Control: 293T , NIH-3T3 , Mouse brain , PC-12 , Rat brain , Jurkat , Raji , 293T , A431 , HeLa , HepG2 , H1299 , HCT116 , MCF-7 , NT2D1 , PC-3 , U87-MG , *Mesenchymal stem cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-HSP70 1A (ABIN2856787)

Chen, Lin, Guo, Chiu, Wu, Jia, Yen: "Rrm2b deletion causes mitochondrial metabolic defects in renal tubules." dans: Scientific reports, Vol. 9, Issue 1, pp. 13238, (2019) (PubMed).

Détails sur HSP70 1A

Antigène: HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))

Autre désignation: HSPA1A (HSPA1A Produits)

Synonymes: anticorps hsp70-4, anticorps hspa1a, anticorps Hsp70-3, anticorps Hsp70.3, anticorps Hsp72, anticorps hsp68, anticorps hsp70A1, anticorps HSP72, anticorps Hsp70-1, anticorps Hspa1, anticorps Hspa1b, anticorps hsp70-1, anticorps hsp70-1a, anticorps hsp70i, anticorps hsp72, anticorps hspa1, anticorps hspa1b, anticorps HSP70-1, anticorps HSP70-1A, anticorps HSP70I, anticorps HSPA1, anticorps HSPA1A, anticorps HSPA1B, anticorps HSP70-2, anticorps HSPA2, anticorps HSP70, anticorps hspA1A, anticorps heat shock cognate 70-kd protein, tandem duplicate 3, anticorps heat shock 70 kDa protein 1, anticorps heat shock 70 kDa protein II, anticorps heat shock protein 1A, anticorps heat shock 70kD protein 1A, anticorps heat shock protein family A (Hsp70) member 1A S homeolog, anticorps heat shock protein family A (Hsp70) member 1A, anticorps heat shock protein 70.2, anticorps heat shock 70kDa protein 1A, anticorps heat shock 70 kDa protein 1B, anticorps heat shock protein 70.1, anticorps hsp70.3, anticorps LOC100023597, anticorps LOC100554002, anticorps LOC100608888, anticorps Hspa1a, anticorps hspa1a.S, anticorps HSPA1A, anticorps HSP70.2, anticorps LOC100354037, anticorps HSP70.1

Sujet: This intronless gene encodes a 70 kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.

Poids moléculaire: 70 kDa

ID gène: 3303

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process