GCM2 anticorps (Center)

N° du produit ABIN2856796

Détail du produit anti-GCM2 anticorps

Antigène: GCM2 (Glial Cells Missing Homolog 2 (GCM2))

Épitope: Center

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GCM2 est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: Rabbit polyclonal antibody to GCM2 (glial cells missing homolog 2 (Drosophila))
GCM2 antibody [N3C3]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human GCM2. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Commentaires:

Positive Control: A431

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.75 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur GCM2

Antigène: GCM2 (Glial Cells Missing Homolog 2 (GCM2))

Autre désignation: GCM2 (GCM2 Produits)

Synonymes: anticorps GCMb, anticorps Gcm-2, anticorps gcm-2, anticorps GCMB, anticorps hGCMb, anticorps Gcm-rs1, anticorps Gcm1, anticorps Gcm1-rs2, anticorps glial cells missing homolog 2, anticorps glial cells missing homolog 2 (Drosophila), anticorps glial cells missing homolog 2 S homeolog, anticorps GCM2, anticorps gcm2, anticorps gcm2.S, anticorps Gcm2

Sujet: This gene is a homolog of the Drosophila glial cells missing gene, which is thought to act as a binary switch between neuronal and glial cell determination. The protein encoded by this gene contains a conserved N-terminal GCM motif that has DNA-binding activity. The protein is a transcription factor that acts as a master regulator of parathyroid development. It has been suggested that this transcription factor might mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. Mutations in this gene are associated with hypoparathyroidism.

Cellular Localization: Nucleus

Poids moléculaire: 57 kDa

ID gène: 9247