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PDE1A anticorps

PDE1A Reactivité: Humain IHC (p), WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2856821
  • Antigène Tous les produits PDE1A
    PDE1A (Calcium/calmodulin-Dependent 3',5'-Cyclic Nucleotide Phosphodiesterase 1A (PDE1A))
    Reactivité
    Humain
    Hôte
    Lapin
    Clonalité
    Polyclonal
    Application
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Rabbit Polyclonal antibody to PDE1A (calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A)
    PDE1A antibody
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Recombinant protein encompassing a sequence within the center region of human PDE1A. The exact sequence is proprietary.
    Isotype
    IgG
  • Indications d'application
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Positive Control: H1299 , HeLa , mouse brain , rat brain

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.74 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Agent conservateur
    Thimerosal (Merthiolate)
    Précaution d'utilisation
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    PDE1A (Calcium/calmodulin-Dependent 3',5'-Cyclic Nucleotide Phosphodiesterase 1A (PDE1A))
    Autre désignation
    phosphodiesterase 1A (PDE1A Produits)
    Synonymes
    anticorps CAM-PDE-1A, anticorps HCAM-1, anticorps HCAM1, anticorps HSPDE1A, anticorps phosphodiesterase 1A, anticorps PDE1A
    Sujet
    Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1, MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109], Fidock et al., 2002 [PubMed 11747989]).[supplied by OMIM]

    Poids moléculaire
    61 kDa
    ID gène
    5136
    UniProt
    P54750
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