BCL2L10 anticorps

N° du produit ABIN2856828

Détail du produit anti-BCL2L10 anticorps

Antigène: BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCL2L10 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain

Attributs du produit: Rabbit polyclonal antibody to BCL2L10 (BCL2-like 10 (apoptosis facilitator))
BCL2L10 antibody [N2C2], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human BCL2L10. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.32 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur BCL2L10

Antigène: BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))

Autre désignation: BCL2 like 10 (BCL2L10 Produits)

Synonymes: anticorps BCL-B, anticorps Boo, anticorps Diva, anticorps AA420380, anticorps AU023065, anticorps C85687, anticorps NR-13, anticorps mcl1l, anticorps nr13, anticorps sb:cb78, anticorps BCL2 like 10, anticorps Bcl2-like 10, anticorps BCL2-like 10 (apoptosis facilitator), anticorps BCL2L10, anticorps Bcl2l10, anticorps bcl2l10

Sujet: The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway.

Cellular Localization: Mitochondrion , Nucleus membrane

Poids moléculaire: 22 kDa

ID gène: 10017

UniProt: Q9HD36

Pathways: Positive Regulation of Endopeptidase Activity