GPER anticorps (C-Term)

N° du produit ABIN2857010

Détail du produit anti-GPER anticorps

Antigène: GPER (G Protein-Coupled Estrogen Receptor 1 (GPER))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPER est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Réactivité croisée: Humain, Porc

Attributs du produit: Rabbit Polyclonal antibody to GPR30 (G protein-coupled estrogen receptor 1)
GPR30 antibody

Purification: Purified by antigen-affinity chromatography.

Classe de qualité: KO Validated

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human GPR30. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: GFP-human GPR30-transfected 293T cells (No boiling)

Validation: KO/KD

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur GPER

Antigène: GPER (G Protein-Coupled Estrogen Receptor 1 (GPER))

Autre désignation: G protein-coupled estrogen receptor 1 (GPER Produits)

Synonymes: anticorps CEPR, anticorps CMKRL2, anticorps DRY12, anticorps FEG-1, anticorps GPCR-Br, anticorps GPER, anticorps GPR30, anticorps LERGU, anticorps LERGU2, anticorps LyGPR, anticorps 6330420K13Rik, anticorps Ceprl, anticorps Gper, anticorps Gpr30, anticorps GPR41, anticorps GPCR30, anticorps G protein-coupled estrogen receptor 1, anticorps GPER1, anticorps GPER, anticorps Gper1

Sujet: This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized.

Cellular Localization: Cell membrane, Multi-pass membrane protein , Endoplasmic reticulum membrane, Multi-pass membrane protein (By similarity) , Golgi apparatus membrane, Multi-pass membrane protein (By similarity)

Poids moléculaire: 42 kDa

ID gène: 2852

UniProt: Q99527

Pathways: EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process