LHCGR anticorps (C-Term)

N° du produit ABIN2857013

Détail du produit anti-LHCGR anticorps

Antigène: LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LHCGR est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris

Attributs du produit: Rabbit Polyclonal antibody to LHR (luteinizing hormone/choriogonadotropin receptor)
LHR antibody [C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human LHR. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: H1299

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-LHCGR (ABIN2857013)

Liu, Hsu, Chen, Chiu, Lin: "A Tri-fusion Reporter Mouse Reveals Tissue-Specific FGF1B Promoter Activity in vivo." dans: Scientific reports, Vol. 9, Issue 1, pp. 11143, (2019) (PubMed).

Wu, Wang, Chueh, Yang, Huang, Lin, Wang, Connolly, Hu, Gomez-Sanchez, Peng, Wu: "The prevalence of CTNNB1 mutations in primary aldosteronism and consequences for clinical outcomes." dans: Scientific reports, Vol. 7, pp. 39121, (2018) (PubMed).

Détails sur LHCGR

Antigène: LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))

Autre désignation: luteinizing hormone/choriogonadotropin receptor (LHCGR Produits)

Synonymes: anticorps HHG, anticorps LCGR, anticorps LGR2, anticorps LH/CG-R, anticorps LH/CGR, anticorps LHR, anticorps LHRHR, anticorps LSH-R, anticorps ULG5, anticorps Gpcr19-rs1, anticorps LH-R, anticorps Lhr, anticorps LSHR, anticorps lhr, anticorps GTHR-II, anticorps zfGTHR-II, anticorps LHCGR, anticorps LOC100222883, anticorps lh-r, anticorps LOC100305044, anticorps luteinizing hormone/choriogonadotropin receptor, anticorps luteinizing hormone/choriogonadotropin receptor L homeolog, anticorps luteinizing hormone receptor, anticorps LHCGR, anticorps Lhcgr, anticorps lhcgr, anticorps lhcgr.L, anticorps lhr, anticorps LOC100305044

Sujet: This gene encodes the receptor for both luteinizing hormone and choriogonadotropin. This receptor belongs to the G-protein coupled receptor 1 family, and its activity is mediated by G proteins which activate adenylate cyclase. Mutations in this gene result in disorders of male secondary sexual character development, including familial male precocious puberty, also known as testotoxicosis, hypogonadotropic hypogonadism, Leydig cell adenoma with precocious puberty, and male pseudohermaphtoditism with Leydig cell hypoplasia.

Cellular Localization: Cell membrane, Multi-pass membrane protein

Poids moléculaire: 79 kDa

ID gène: 3973

UniProt: P22888

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, cAMP Metabolic Process, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling