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CXCR7 anticorps

KO Validated CXCR7 Reactivité: Humain WB, ELISA, FACS, IHC (p), IF, IHC (fro), IP, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2857021
  • Antigène Voir toutes CXCR7 Anticorps
    CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))
    Reactivité
    • 100
    • 45
    • 42
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 83
    • 16
    • 1
    Lapin
    Clonalité
    • 75
    • 24
    • 1
    Polyclonal
    Conjugué
    • 40
    • 7
    • 7
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CXCR7 est non-conjugé
    Application
    • 66
    • 37
    • 34
    • 16
    • 14
    • 13
    • 13
    • 8
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Immunocytochemistry (ICC)
     Réactivité croisée
    Humain, Souris
    Attributs du produit
    Rabbit Polyclonal antibody to CXCR7 (C-X-C chemokine receptor type 7)
    CXCR7 antibody [C1C2], Internal
    Purification
    Purified by antigen-affinity chromatography.
    Classe de qualité
    KO Validated
    Immunogène
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human CXCR7. The exact sequence is proprietary.
    Isotype
    IgG
  • Indications d'application
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Validatio: KO/KD, Orthogonal

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.92 mg/mL
    Buffer
    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Wei, Huang, Hsieh, Lin, Shyu, Chen, Hsieh: "Atypical chemokine receptor ACKR3/CXCR7 controls postnatal vasculogenesis and arterial specification by mesenchymal stem cells via Notch signaling." dans: Cell death & disease, Vol. 11, Issue 5, pp. 307, (2020) (PubMed).

    Liu, Song, Setroikromo, Chen, Hu, Chen, van der Wekken, Melgert, Timens, van den Berg, Saber, Haisma: "CX Chemokine Receptor 7 Contributes to Survival of KRAS-Mutant Non-Small Cell Lung Cancer upon Loss of Epidermal Growth Factor Receptor." dans: Cancers, Vol. 11, Issue 4, (2019) (PubMed).

    Xu, Tang, Wang, Liu, Fu, Luo: "CXCR7 promotes melanoma tumorigenesis via Src kinase signaling." dans: Cell death & disease, Vol. 10, Issue 3, pp. 191, (2019) (PubMed).

    Tam, Ko, Koon, Cheng, Lok, Lau, Leung, Fung, Chan, Lau: "Identification of Target Genes Involved in Wound Healing Angiogenesis of Endothelial Cells with the Treatment of a Chinese 2-Herb Formula." dans: PLoS ONE, Vol. 10, Issue 10, pp. e0139342, (2016) (PubMed).

    Liu, Carson-Walter, Walter: "Chemokine receptor CXCR7 is a functional receptor for CXCL12 in brain endothelial cells." dans: PLoS ONE, Vol. 9, Issue 8, pp. e103938, (2015) (PubMed).

    Salazar, Muñoz, Kallifatidis, Singh, Jordà, Lokeshwar: "The chemokine receptor CXCR7 interacts with EGFR to promote breast cancer cell proliferation." dans: Molecular cancer, Vol. 13, pp. 198, (2014) (PubMed).

    Singh, Lokeshwar: "The IL-8-regulated chemokine receptor CXCR7 stimulates EGFR signaling to promote prostate cancer growth." dans: Cancer research, Vol. 71, Issue 9, pp. 3268-77, (2011) (PubMed).

  • Antigène
    CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))
    Autre désignation
    atypical chemokine receptor 3 (CXCR7 Produits)
    Synonymes
    anticorps CMKOR1, anticorps CXC-R7, anticorps CXCR-7, anticorps CXCR7, anticorps GPR159, anticorps RDC-1, anticorps RDC1, anticorps AW541270, anticorps Cmkor1, anticorps Cxcr7, anticorps Rdc1, anticorps ackr3, anticorps cxcr7, anticorps rdc1, anticorps xcxcr7, anticorps atypical chemokine receptor 3, anticorps ORF 74; similar to Kaposi's sarcoma-associated herpesvirus ORF 74, anticorps atypical chemokine receptor 3 L homeolog, anticorps ACKR3, anticorps MmrVgp88, anticorps Ackr3, anticorps ackr3.L
    Sujet
    This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas.

    Cellular Localization: Cell membrane
    Poids moléculaire
    41 kDa
    ID gène
    57007
    UniProt
    P25106
    Pathways
    Myometrial Relaxation and Contraction, Negative Regulation of intrinsic apoptotic Signaling
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