RORA anticorps
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- Antigène Voir toutes RORA Anticorps
- RORA (RAR-Related Orphan Receptor A (RORA))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp RORA est non-conjugé
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Application
- Western Blotting (WB)
- Réactivité croisée
- Humain, Souris, Rat
- Attributs du produit
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Rabbit Polyclonal antibody to ROR alpha (RAR-related orphan receptor A)
ROR alpha antibody [N2N3] - Purification
- Purified by antigen-affinity chromatography.
- Classe de qualité
- KO Validated
- Immunogène
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human ROR alpha. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product RORA Anticorps primaire
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- Indications d'application
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Commentaires
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Positive Control: Mouse brain , HeLa , NIH-3T3
Validation: KO/KD
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- Agent conservateur
- Thimerosal (Merthiolate)
- Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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LncRNA-p21 alters the antiandrogen enzalutamide-induced prostate cancer neuroendocrine differentiation via modulating the EZH2/STAT3 signaling." dans: Nature communications, Vol. 10, Issue 1, pp. 2571, (2019) (PubMed).
: "RORα and RORγ expression inversely correlates with human melanoma progression." dans: Oncotarget, Vol. 7, Issue 39, pp. 63261-63282, (2018) (PubMed).
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LncRNA-p21 alters the antiandrogen enzalutamide-induced prostate cancer neuroendocrine differentiation via modulating the EZH2/STAT3 signaling." dans: Nature communications, Vol. 10, Issue 1, pp. 2571, (2019) (PubMed).
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- Antigène
- RORA (RAR-Related Orphan Receptor A (RORA))
- Autre désignation
- RAR related orphan receptor A (RORA Produits)
- Sujet
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The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene.
- Poids moléculaire
- 63 kDa
- ID gène
- 6095
- UniProt
- P35398
- Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
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