BAK1 anticorps (N-Term)
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- Antigène Voir toutes BAK1 Anticorps
- BAK1 (BCL2-Antagonist/killer 1 (BAK1))
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Épitope
- N-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BAK1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Réactivité croisée
- Humain
- Attributs du produit
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Rabbit Polyclonal antibody to BAK (BCL2-antagonist/killer 1)
BAK antibody [N1N2], N-term - Purification
- Purified by antigen-affinity chromatography.
- Immunogène
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human BAK. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product BAK1 Anticorps primaire
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- Indications d'application
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Commentaires
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Validation: Orthogonal
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- Agent conservateur
- Thimerosal (Merthiolate)
- Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Antigène
- BAK1 (BCL2-Antagonist/killer 1 (BAK1))
- Autre désignation
- BCL2 antagonist/killer 1 (BAK1 Produits)
- Synonymes
- anticorps BAK, anticorps BAK-LIKE, anticorps BCL2L7, anticorps CDN1, anticorps Bak, anticorps N-BAK1, anticorps N-Bak, anticorps Bak1, anticorps bak, anticorps bak1, anticorps BCL2 antagonist/killer 1, anticorps BCL2-antagonist/killer 1, anticorps BCL2 antagonist/killer 1 L homeolog, anticorps BAK1, anticorps Bak1, anticorps bak1.L
- Sujet
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The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
Cellular Localization: Membrane - Poids moléculaire
- 23 kDa
- ID gène
- 578
- UniProt
- Q16611
- Pathways
- Apoptose, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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