8-OHDG anticorps

N° du produit ABIN285804

Détail du produit anti-8-OHDG anticorps

Antigène: 8-OHDG (8-Hydroxyguanosine (8-OHDG))

Reactivité: Veuillez nous consulter SVP

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp 8-OHDG est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Immunogène: 8-Hydroxyguanosine antibody was raised in goat using 8-Hydroxyguansoine as the immunogen.

Information d'application

Indications d'application: ELISA: >1:250,000, IHC-P: >1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as liquid whole serum without preservative

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles

Stock: -20 °C

Stockage commentaire: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Références pour anticorps anti-8-OHDG (ABIN285804)

Tuerdi, Kikuta, Kinoshita, Kamogashira, Kondo, Yamasoba: "Zone-specific damage of the olfactory epithelium under protein restriction." dans: Scientific reports, Vol. 10, Issue 1, pp. 22175, (2021) (PubMed).

Jeannot, Pogribny, Beland, Rusyn: "Chronic administration of ethanol leads to an increased incidence of hepatocellular adenoma by promoting H-ras-mutated cells." dans: Cancer letters, Vol. 301, Issue 2, pp. 161-7, (2011) (PubMed).

Détails sur 8-OHDG

Antigène: 8-OHDG (8-Hydroxyguanosine (8-OHDG))

Abstract: 8-OHDG Produits

Classe de substances: Chemical

Sujet: 8-Hydroxydeoxyguanosine (8OHdG) is a modified base that occurs in DNA due to attack by hydroxyl radicals that are formed as byproducts and intermediates of aerobic metabolism and during oxidative stress. There is increasing evidence to support the involvement of free radical reactions in the damage of biomolecules that eventually leads to several diseases in humans, such as arteriosclerosis, cerebral and heart ischemia-reperfusion injury, cancer, rheumatoid arthritis, inflammation, diabetes, aging, and neurodegenerative conditions, such as Alzheimer?s disease.