The OTR peptide is 100% conserved in Rat, 95% in Mouse, 89% in Sheep, 85% inHuman/monkey, 78% in Bovine, 80% in Pig. Antibody crossreactitivy in various species is no established.
Réactivité croisée (Details)
This OTR11 peptide sequence is 95 % conserved in mouse, 89 % in sheep, 85 % in human/monkey, 78 % with bovine, and 80 % with pig OTR.
Purification
Affinity chromatography purified
Immunogène
Oxytocin receptor antibody was raised in rabbit using a 20 amino acid peptide of rat OTR as the immunogen.
The oxytocin receptor, also known as OXTR, is a protein which functions as receptor for the hormone and neurotransmitter oxytocin. In humans, the oxytocin receptor is encoded by the OXTR gene, which has been localized to human chromosome 3p25. The OXTR protein belongs to the G-protein coupled receptor family, specifically Gq, and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate several different second messenger systems.