Suitable for use in Dot blot, ELISA (1/10,000) and Western blot. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
1.5 mg/mL (OD280nm, E0.1%=1.4)
Buffer
1x PBS, pH 7.2 containing 20 % Glycerol and no preservative.
anticorps bna, anticorps botA, anticorps botulinum neurotoxin type A, anticorps atx
Sujet
Clostridium botulinum neurotoxins are zinc-dependent proteases that block the release of acetylcholine from peripheral cholinergic nerve endings by targeting specific membrane proteins including synaptosomal-associated proteins (SNAP), vesicle-associated membrane proteins (VAMP), and syntaxins. Neurotoxin A is characteristically associated with human botulism and known to target and hydrolyse the 197-Gln-|-Arg-198 bond of SNAP-25.Synonyms: BOTOX, BoNT/A, Bontoxilysin-A, Clostridium botulinum Toxin A