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Choline Acetyltransferase anticorps (N-Term) (HRP)

CHAT Reactivité: Humain WB, IF, ICC Hôte: Lapin Polyclonal HRP
N° du produit ABIN2869107
  • Antigène Voir toutes Choline Acetyltransferase (CHAT) Anticorps
    Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))
    Épitope
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    N-Term
    Reactivité
    • 70
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    Humain
    Hôte
    • 65
    • 5
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    Lapin
    Clonalité
    • 70
    • 12
    Polyclonal
    Conjugué
    • 41
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    Cet anticorp Choline Acetyltransferase est conjugé à/à la HRP
    Application
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    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    Predicted molecular weight at ~82.5 kDa. Observed molecular weights between 68-70 kDa.
     Réactivité croisée
    Humain, Souris
    Purification
    Peptide Affinity Purified
    Immunogène
    Synthetic peptide from the N-terminal to the mid-protein of human Choline O-Acetyltrasferase
    Top Product
    Discover our top product CHAT Anticorps primaire
  • Indications d'application
    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    Commentaires

    A 1:1000 dilution of ABIN2869107 was sufficient for detection of Choline Acetyltransferase on mouse brain lysates using Goat anti-rabbit IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Conjugated antibodies should be stored at 4°C
  • Antigène
    Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))
    Autre désignation
    Choline Acetyltransferase (CHAT Produits)
    Synonymes
    anticorps CHOACTASE, anticorps CMS1A, anticorps CMS1A2, anticorps ChoAcTase, anticorps B230380D24Rik, anticorps choline O-acetyltransferase, anticorps choline O-acetyltransferase a, anticorps choline acetyltransferase, anticorps carnitine O-acetyltransferase, anticorps CHAT, anticorps chata, anticorps Chat, anticorps PGTG_00551, anticorps LOC100533322
    Sujet
    Acetylcholine (ACh) is a common neurotransmitter for motoneurons, preganglionic autonomic neurons, postganglionic parasympathetic neurons, a variety of brain regions and some emerging neuron-like stem cells. The metabolism of Ach is relatively simple, involving only two enzymes: choline acetyltransferase (ChAT) for synthesis and acetylcholinesterase (AChE) for degradation. Further, acetylcholine has little function in neurons other than neurotransmission and seems to be neuron specific. It seems that only cholinergic neurons have significant amounts of ChAT making anti-choline acetyltransferase a useful specific marker. ChAT is a valuable marker for diseases associated with decreased cholinergic function such as Schizophrenia, Alzheimer disease and Down syndrome (1-3).
    ID gène
    1103
    NCBI Accession
    NP_001136401
    UniProt
    P28329
    Pathways
    Skeletal Muscle Fiber Development
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