Cet anticorp Cholesterol Esterase est conjugé à/à la Biotin
Application
ELISA, Immunohistochemistry (IHC)
Purification
The splenic lymphocytes from BALB/c mouse, immunized with CEL-BSA were fused to myelomaP3U1 cells. The cell line (KNH-30) with positive reaction was grown in ascitic fluid of BALB/cmouse, from which the antibody was purified by Protein G affinity chromatography and conjugated.
Reaction of protein amino groups with glucose leads, through the early products such as a Schiff base andAmadori rearrangement products, to the formation of advanced glycation end products (AGEs). Recentimmunological studies using anti-AGEs antibody (6D12) demonstrated the presence of AGEs-modified proteinsin several human tissues: human lens (nondiabetic and noncataractous), renal proximal tubules inpatients with diabetic nephropathy and chronic renal failure, diabetic retina, peripheral nerves ofdiabetic neuropathy, atherosclerotic lesions of arterial walls, beta2-microglobulin forming amyloid fibrilsin patients with hemodialysis-related amyloidosis, senile plaques of patients with Alzheimer