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ICAM2 anticorps (PE)

ICAM2 Reactivité: Humain FACS Hôte: Souris Monoclonal CBR-IC2-2 PE
N° du produit ABIN2967163
  • Antigène Voir toutes ICAM2 Anticorps
    ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))
    Reactivité
    • 66
    • 30
    • 20
    Humain
    Hôte
    • 53
    • 18
    • 16
    Souris
    Clonalité
    • 54
    • 32
    Monoclonal
    Conjugué
    • 43
    • 8
    • 8
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ICAM2 est conjugé à/à la PE
    Application
    • 53
    • 50
    • 25
    • 21
    • 20
    • 14
    • 13
    • 13
    • 7
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificité
    The mouse monoclonal antibody CBR-IC2/2 recognizes an extracellular epitope of CD102 (ICAM-2), an approximately 55 kDa type I transmembrane glycoprotein expressed mainly on vascular endothelial cells and folicular dendritic cells, in lower amount on lymphocytes, monocytes and platelets.
    Réactivité croisée (Details)
    Human
    Purification
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogène
    Human CD102 cDNA transfected COS cells
    Clone
    CBR-IC2-2
    Isotype
    IgG2a
    Top Product
    Discover our top product ICAM2 Anticorps primaire
  • Indications d'application
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    Commentaires

    The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    Restrictions
    For Research Use only
  • Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Antigène
    ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))
    Autre désignation
    CD102 / ICAM-2 (ICAM2 Produits)
    Synonymes
    anticorps ICAM2, anticorps CD102, anticorps Icam-2, anticorps Ly-60, anticorps intercellular adhesion molecule 2, anticorps LOC506088, anticorps ICAM2, anticorps LOC616254, anticorps LOC100140873, anticorps Icam2
    Sujet
    Intercellular adhesion molecule 2,CD102 / ICAM-2 (intracellular cell adhesion molecule-2), a counter receptor of LFA-1 (CD11a/CD18), is a transmembrane glycoprotein with two extracellular IgC-like domains and intracellular C-terminal tail. It is involved in lymphocyte recirculation and homing to the sites of inflammation. Through interaction with integrins it provides to the immune cells costimulatory signals. Expression of CD102 on blood cells (lymphocytes, monocytes, thrombocytes) is lower than on endothelium and follicular dendritic cells. CD102 levels are upregulated in lymph nodes with malignant infiltration.,ICAM2
    ID gène
    3384
    UniProt
    P13598
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