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CXCR4 anticorps
CXCR4
Reactivité: Humain, Non-Human Primate
FACS, IHC (p), ICC
Hôte: Souris
Monoclonal
12G5
unconjugated
N° du produit ABIN2967165
Détail du produit anti-CXCR4 anticorps
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Antigène
Voir toutes CXCR4 Anticorps
CXCR4
(Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
Reactivité
Toutes les réactivités sur CXCR4 Anticorps
Humain, Non-Human Primate
Hôte
Toutes les hôtes sur CXCR4 Anticorps
Souris
Clonalité
Toutes les clonalités sur CXCR4 Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers CXCR4 Anticorps
Cet anticorp CXCR4 est non-conjugé
Application
Tous les applications à travers CXCR4 Anticorps.
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
Specificité
The mouse monoclonal antibody 12G5 recognizes an extracellular epitope of CD184, a 45 kDa G-protein-linked CXC chemokine receptor widely expressed on blood and tissue cells.
Réactivité croisée (Details)
Human, Non-Human Primates
Purification
Purified by protein-A affinity chromatography.
Pureté
> 95 % (by SDS-PAGE)
Immunogène
CP-MAC-infected Sup-T1 cells
Clone
12G5
Isotype
IgG2a kappa
Top Product
Discover our top product CXCR4 Anticorps primaire
Alternatives
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Information d'application
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Indications d'application
Flow cytometry: Recommended dilution: 2-4 μg/mL.
Restrictions
For Research Use only
Stockage
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Concentration
1 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C
Stockage commentaire
Store at 2-8°C. Do not freeze.
Détails sur CXCR4
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Antigène
CXCR4
(Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
Autre désignation
CD184 / CXCR4 (CXCR4 Produits )
Synonymes
anticorps CD184, anticorps D2S201E, anticorps FB22, anticorps HM89, anticorps HSY3RR, anticorps LAP3, anticorps LCR1, anticorps LESTR, anticorps NPY3R, anticorps NPYR, anticorps NPYRL, anticorps NPYY3R, anticorps WHIM, anticorps Cmkar4, anticorps PB-CKR, anticorps PBSF/SDF-1, anticorps Sdf1r, anticorps CXC-R4-B, anticorps CXCR-4-B, anticorps cd184, anticorps cxcr4, anticorps fb22, anticorps hm89, anticorps hsy3rr, anticorps lap3, anticorps lcr1, anticorps lestr, anticorps npy3r, anticorps npyr, anticorps npyrl, anticorps npyy3r, anticorps xcxcr4, anticorps CXC-R4, anticorps CXCR-4, anticorps d2s201e, anticorps whim, anticorps CXC-R4-A, anticorps CXCR-4-A, anticorps xCXCR4, anticorps CXCR4, anticorps cb403, anticorps zgc:109863, anticorps cb824, anticorps C-X-C motif chemokine receptor 4, anticorps chemokine (C-X-C motif) receptor 4, anticorps C-X-C motif chemokine receptor 4 S homeolog, anticorps C-X-C chemokine receptor type 4, anticorps C-X-C motif chemokine receptor 4 L homeolog, anticorps chemokine (C-X-C motif), receptor 4b, anticorps chemokine (C-X-C motif) receptor 4a, anticorps CXCR4, anticorps Cxcr4, anticorps cxcr4.S, anticorps cxcr4, anticorps LOC100049444, anticorps cxcr4.L, anticorps cxcr4b, anticorps cxcr4a
Sujet
C-X-C motif chemokine receptor 4,CD184, also known as CXCR4 or fusin, is a receptor for the C-X-C chemokine SDF-1. It is expressed mainly in hematopoietic cells, vascular endothelium, and neural tissue. CD184 is a G-protein coupled receptor containing extracellular N-terminal, seven transmembrane domains and intracellular C-terminal domain. It transduces signal by increasing the intracellular calcium level. CD184 plays an essential role in vascularization of the gastrointestinal tract, and is involved in cerebellar development and in hematopoiesis. It is also a coreceptor (with CD4) for HIV-1 X4 virus and a primary receptor for some HIV-2 isolates.,CXCR4, LAP3, LCR1, HM89, fusin, SDF1R
ID gène
7852
UniProt
P61073
Pathways
Regulation of Cell Size , CXCR4-mediated Signaling Events
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