CCL20 anticorps (PE-DyLight 594)

N° du produit ABIN2967173

Détail du produit anti-CCL20 anticorps (PE-DyLight 594)

Antigène: CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CCL20 est conjugé à/à la PE-DyLight 594

Application: Flow Cytometry (FACS)

Specificité: The antibody UCHL1 recognizes an extracellular epitope of CD45R0, a 180 kDa low molecular weight isoform of the leukocyte common antigen (LCA). The antigen is expressed on a subset of memory/activated T cells and on cortical thymocytes.

Réactivité croisée (Details): Human

Purification: Purified antibody is conjugated with activated tandem dye of R-phycoerythrin-DyLight®594 (PE-DyLight®594) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogène: Human IL-2 dependent T cells

Clone: UCHL1

Isotype: IgG2a

Information d'application

Indications d'application: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.

Commentaires:

The purified antibody is conjugated with tandem dye PE-DyLight™, 594 (PE-DL594) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

Restrictions: For Research Use only

Stockage

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Détails sur CCL20

Antigène: CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))

Autre désignation: CD45R0 (CCL20 Produits)

Synonymes: anticorps MIP-3ALPHA, anticorps CCL20, anticorps si:dkey-150o13.1, anticorps CKb4, anticorps LARC, anticorps MIP-3-alpha, anticorps MIP-3a, anticorps MIP3A, anticorps SCYA20, anticorps ST38, anticorps MIP-3A, anticorps MIP-3[a], anticorps Scya20, anticorps exodus-1, anticorps C-C motif chemokine ligand 20, anticorps chemokine (C-C motif) ligand 20b, anticorps chemokine (C-C motif) ligand 20, anticorps CCL20, anticorps ccl20b, anticorps Ccl20

Sujet: CD45R0 is the shortest isoform of a receptor-type protein tyrosine phosphatase, CD45 glycoprotein. CD45 is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45 isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. These isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45R0 is expressed e.g. on macrophages, CD8+ T cells, activated T cells and myeloma cells.,PTPRCR, T200R0

Pathways: Phosphorylation & l'infection par le SRAS-CoV-2