OPTN anticorps (AA 1-577)

N° du produit ABIN3015613

Détail du produit anti-OPTN anticorps

Antigène: OPTN (Optineurin (OPTN))

Épitope: AA 1-577

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OPTN est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Séquence: MSHQPLSCLT EKEDSPSEST GNGPPHLAHP NLDTFTPEEL LQQMKELLTE NHQLKEAMKL NNQAMKGRFE ELSAWTEKQK EERQFFEIQS KEAKERLMAL SHENEKLKEE LGKLKGKSER SSEDPTDDSR LPRAEAEQEK DQLRTQVVRL QAEKADLLGI VSELQLKLNS SGSSEDSFVE IRMAEGEAEG SVKEIKHSPG PTRTVSTGTA LSKYRSRSAD GAKNYFEHEE LTVSQLLLCL REGNQKVERL EVALKEAKER VSDFEKKTSN RSEIETQTEG STEKENDEEK GPETVGSEVE ALNLQVTSLF KELQEAHTKL SEAELMKKRL QEKCQALERK NSAIPSELNE KQELVYTNKK LELQVESMLS EIKMEQAKTE DEKSKLTVLQ MTHNKLLQEH NNALKTIEEL TRKESEKVDR AVLKELSEKL ELAEKALASK QLQMDEMKQT IAKQEEDLET MTILRAQMEV YCSDFHAERA AREKIHEEKE QLALQLAVLL KENDAFEDGG RQSLMEMQSR HGARTSDSDQ QAYLVQRGAE DRDWRQQRNI PIHSCPKCGE VLPDIDTLQI HVMDCII

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-577 of human OPTN (NP_068815.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur OPTN

Antigène: OPTN (Optineurin (OPTN))

Autre désignation: OPTN (OPTN Produits)

Synonymes: anticorps nrp, anticorps fip2, anticorps hip7, anticorps hypl, anticorps glc1e, anticorps tfiiia-intp, anticorps ALS12, anticorps FIP2, anticorps GLC1E, anticorps HIP7, anticorps HYPL, anticorps NRP, anticorps TFIIIA-INTP, anticorps Fip2, anticorps 4930441O07Rik, anticorps fj52f04, anticorps si:ch211-240l19.3, anticorps wu:fj52f04, anticorps zgc:66386, anticorps zgc:77868, anticorps optineurin, anticorps optineurin L homeolog, anticorps OPTN, anticorps optn, anticorps Optn, anticorps optn.L

Sujet: This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.,OPTN,ALS12,FIP2,GLC1E,HIP7,HYPL,NRP,TFIIIA-INTP,Signal Transduction,Immunology & Inflammation,Cytokines,TNF,Cell Intrinsic Innate Immunity Signaling Pathway,Neuroscience,OPTN

Poids moléculaire: 59 kDa/65 kDa

ID gène: 10133

UniProt: Q96CV9

Pathways: M Phase