Histone 3 anticorps (H3K9me3)

N° du produit ABIN3016030

Détail du produit anti-Histone 3 anticorps

Antigène: Histone 3 (H3)

Épitope: H3K9me3

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Histone 3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP), Dot Blot (DB)

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Methylated Antibodies

Purification: Affinity purification

Immunogène: A synthetic methylated peptide corresponding to residues surrounding K9 of human histone H3

Isotype: IgG

Information d'application

Indications d'application: DB,1:500 - 1:2000,WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,ChIP,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-Histone 3 (ABIN3016030)

Zuo, Rong, Li, Lv, Lan, Tong: "The histone methyltransferase SETD2 is required for expression of acrosin-binding protein 1 and protamines and essential for spermiogenesis in mice." dans: The Journal of biological chemistry, Vol. 293, Issue 24, pp. 9188-9197, (2019) (PubMed).

Zhao, Zhang, Chen, Wang, Li, Cheng, Duan, Zhu, Wei, Li, Wu, Han, Yu, Gao, Li, Wong: "Dissecting the precise role of H3K9 methylation in crosstalk with DNA maintenance methylation in mammals." dans: Nature communications, Vol. 7, pp. 12464, (2018) (PubMed).

Fan, Lv, Huo, Wu, Wang, Cheng, Liu, Tang, Zhang, Zhang, Zheng, Wu, Wen: "The nuclear matrix protein HNRNPU maintains 3D genome architecture globally in mouse hepatocytes." dans: Genome research, Vol. 28, Issue 2, pp. 192-202, (2018) (PubMed).

Yu, Liu, Liu, Wang, Liu, Miao, Du, Yang: "Ascorbic acid induces global epigenetic reprogramming to promote meiotic maturation and developmental competence of porcine oocytes." dans: Scientific reports, Vol. 8, Issue 1, pp. 6132, (2018) (PubMed).

Cao, Liu, Yue, Liu, Pei, Gu, Wang, Jia: "Iron chelation inhibits cancer cell growth and modulates global histone methylation status in colorectal cancer." dans: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, Vol. 31, Issue 5, pp. 797-805, (2018) (PubMed).

Yin, Jiang, Jiang, Gao, Wang, Fan, Khan, Jabeen, Khan, Ali, Xu, Pandita, Fan, Zhang, Shi: "Histone acetyltransferase KAT8 is essential for mouse oocyte development by regulating reactive oxygen species levels." dans: Development (Cambridge, England), Vol. 144, Issue 12, pp. 2165-2174, (2017) (PubMed).

Zhao, Lei, Zhang, Zheng, Wang, Zhao, Li, Ye, Li, Wei, Wu: "Global histone modification profiling reveals the epigenomic dynamics during malignant transformation in a four-stage breast cancer model." dans: Clinical epigenetics, Vol. 8, pp. 34, (2016) (PubMed).

Détails sur Histone 3

Antigène: Histone 3 (H3)

Autre désignation: Histone H3 (H3 Produits)

Synonymes: anticorps H-3, anticorps histocompatibility 3, anticorps H3

Sujet: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.,H3.4,H3/g,H3FT,H3t,HIST3H3,Histone H3,HIST1H3A,Signal Transduction,MAPK-Erk Signaling Pathway,MAPK-P38 Signaling Pathway,Epigenetics & Nuclear Signaling,Epigenetic Modifications,Methylation,Histone H3

Poids moléculaire: 15 kDa

ID gène: 8290

UniProt: Q16695