TIM3 anticorps (AA 22-202)

N° du produit ABIN3016173

Détail du produit anti-TIM3 anticorps

Antigène: TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))

Épitope: AA 22-202

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TIM3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: SEVEYRAEVG QNAYLPCFYT PAAPGNLVPV CWGKGACPVF ECGNVVLRTD ERDVNYWTSR YWLNGDFRKG DVSLTIENVT LADSGIYCCR IQIPGIMNDE KFNLKLVIKP AKVTPAPTRQ RDFTAAFPRM LTTRGHGPAE TQTLGSLPDI NLTQISTLAN ELRDSRLAND LRDSGATIRI G

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 22-202 of human TIM-3/HAVCR2 (NP_116171.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:1000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TIM3

Antigène: TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))

Autre désignation: HAVCR2 (TIM 3 Produits)

Synonymes: anticorps HAVCR2, anticorps MGC140131, anticorps HAVcr-2, anticorps KIM-3, anticorps TIM3, anticorps TIMD-3, anticorps TIMD3, anticorps Tim-3, anticorps TIM-3, anticorps Tim3, anticorps Timd3, anticorps tim3, anticorps hepatitis A virus cellular receptor 2, anticorps HAVCR2, anticorps Havcr2

Classe de substances: Virus

Sujet: The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.,HAVCR2,CD366,HAVcr-2,KIM-3,TIM3,TIMD-3,TIMD3,Tim-3,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,HAVCR2

Poids moléculaire: 16 kDa/33 kDa

ID gène: 84868

UniProt: Q8TDQ0

Pathways: Regulation of Lipid Metabolism by PPARalpha, Cancer Immune Checkpoints