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DNASE1 anticorps (AA 22-282)
DNASE1
Reactivité: Humain
WB
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN3016215
Détail du produit anti-DNASE1 anticorps
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Antigène
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DNASE1
(Deoxyribonuclease I (DNASE1))
Épitope
Tous les épitopes à travers DNASE1 Anticorps.
AA 22-282
Reactivité
Toutes les réactivités sur DNASE1 Anticorps
Humain
Hôte
Toutes les hôtes sur DNASE1 Anticorps
Lapin
Clonalité
Toutes les clonalités sur DNASE1 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers DNASE1 Anticorps
Cet anticorp DNASE1 est non-conjugé
Application
Tous les applications à travers DNASE1 Anticorps.
Western Blotting (WB)
Séquence
SLKIAAFNIQ TFGETKMSNA TLVSYIVQIL SRYDIALVQE VRDSHLTAVG KLLDNLNQDA PDTYHYVVSE PLGRNSYKER YLFVYRPDQV SAVDSYYYDD GCEPCGNDTF NREPAIVRFF SRFTEVREFA IVPLHAAPGD AVAEIDALYD VYLDVQEKWG LEDVMLMGDF NAGCSYVRPS QWSSIRLWTS PTFQWLIPDS ADTTATPTHC AYDRIVVAGM LLRGAVVPDS ALPFNFQAAY GLSDQLAQAI SDHYPVEVML K
Réactivité croisée
Humain, Souris, Rat
Attributs du produit
Polyclonal Antibodies
Purification
Affinity purification
Immunogène
Recombinant fusion protein containing a sequence corresponding to amino acids 22-282 of human DNASE1 (NP_005214.2).
Isotype
IgG
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Information d'application
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Indications d'application
WB,1:500 - 1:2000
Restrictions
For Research Use only
Stockage
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Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Détails sur DNASE1
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Antigène
DNASE1
(Deoxyribonuclease I (DNASE1))
Autre désignation
DNASE1 (DNASE1 Produits )
Synonymes
anticorps LOC397802, anticorps DNL1, anticorps DRNI, anticorps AI788650, anticorps DNaseI, anticorps Dnl1, anticorps dnase1-A, anticorps zgc:92440, anticorps DNase I, anticorps deoxyribonuclease 1, anticorps deoxyribonuclease I, anticorps deoxyribonuclease I L homeolog, anticorps Deoxyribonuclease I, anticorps endA, anticorps LOC397802, anticorps DNASE1, anticorps Dnase1, anticorps dnase1.L, anticorps dnase1, anticorps CpipJ_CPIJ011184, anticorps CpipJ_CPIJ011185, anticorps CpipJ_CPIJ011186, anticorps CpipJ_CPIJ011187, anticorps CpipJ_CPIJ011190, anticorps CpipJ_CPIJ017803, anticorps Desal_1409, anticorps MPET_RS05255, anticorps METEV_RS02275, anticorps Plabr_0631
Sujet
This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.,DNASE1,DNL1,DRNI,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Endocrine & Metabolism,DNASE1
Poids moléculaire
19 kDa/31 kDa
ID gène
1773
UniProt
P24855
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