Metabotropic Glutamate Receptor 3 anticorps (AA 23-170)

N° du produit ABIN3016218

Détail du produit anti-Metabotropic Glutamate Receptor 3 anticorps

Antigène: Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))

Épitope: AA 23-170

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Metabotropic Glutamate Receptor 3 est non-conjugé

Application: Western Blotting (WB)

Séquence: LGDHNFLRRE IKIEGDLVLG GLFPINEKGT GTEECGRINE DRGIQRLEAM LFAIDEINKD DYLLPGVKLG VHILDTCSRD TYALEQSLEF VRASLTKVDE AEYMCPDGSY AIQENIPLLI AGVIGGSYSS VSIQVANLLR LFQIPQIS

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 23-170 of human GRM3 (NP_000831.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Metabotropic Glutamate Receptor 3

Antigène: Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))

Autre désignation: GRM3 (GRM3 Produits)

Synonymes: anticorps GLUR3, anticorps GPRC1C, anticorps MGLUR3, anticorps mGlu3, anticorps 0710001G23Rik, anticorps Gprc1c, anticorps mGluR3, anticorps glutamate metabotropic receptor 3, anticorps glutamate receptor, metabotropic 3, anticorps GRM3, anticorps Grm3

Sujet: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.,GRM3,GLUR3,GPRC1C,MGLUR3,mGlu3,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,GRM3

Poids moléculaire: 60 kDa/98 kDa

ID gène: 2913

UniProt: Q14832

Pathways: cAMP Metabolic Process, Synaptic Membrane