CNTF Receptor alpha anticorps (AA 190-340)

N° du produit ABIN3016492

Détail du produit anti-CNTF Receptor alpha anticorps

Antigène: CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))

Épitope: AA 190-340

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CNTF Receptor alpha est non-conjugé

Application: Western Blotting (WB)

Séquence: NATAITFDEF TIVKPDPPEN VVARPVPSNP RRLEVTWQTP STWPDPESFP LKFFLRYRPL ILDQWQHVEL SDGTAHTITD AYAGKEYIIQ VAAKDNEIGT WSDWSVAAHA TPWTEEPRHL TTEAQAAETT TSTTSSLAPP PTTKICDPGE L

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 190-340 of human CNTFR (NP_001833.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:400 - 1:2000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-CNTF Receptor alpha (ABIN3016492)

Yong, Groeger, von Bremen, Ruf: "Ciliary Neurotrophic Factor (CNTF) and Its Receptors Signal Regulate Cementoblasts Apoptosis through a Mechanism of ERK1/2 and Caspases Signaling." dans: International journal of molecular sciences, Vol. 23, Issue 15, (2022) (PubMed).

Détails sur CNTF Receptor alpha

Antigène: CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))

Autre désignation: CNTFR (CNTFR Produits)

Synonymes: anticorps CNTFR-alpha, anticorps CNTFRALPHA, anticorps Cntfralpha, anticorps cb549, anticorps fj33e02, anticorps sb:cb549, anticorps wu:fj33e02, anticorps si:bz76a6.1, anticorps si:dz248f2.1, anticorps si:rp71-76a6.1, anticorps ciliary neurotrophic factor receptor, anticorps ciliary neurotrophic factor receptor L homeolog, anticorps CNTFR, anticorps cntfr.L, anticorps Cntfr, anticorps cntfr

Sujet: This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene.,CNTFR,Signal Transduction,Neuroscience,CNTFR

Poids moléculaire: 40 kDa

ID gène: 1271

UniProt: P26992

Pathways: Signalistation JAK/STAT, Feeding Behaviour