Bcl-2 anticorps (AA 81-131)

N° du produit ABIN3016826

Détail du produit anti-Bcl-2 anticorps

Antigène: Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Épitope: AA 81-131

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Bcl-2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Séquence: AAGPALSPVP PVVHLTLRQA GDDFSRRYRR DFAEMSSQLH LTPFTARGRF A

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 81-131 of human Bcl-2 (NP_000624.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:1000,IF,1:50 - 1:100,IP,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-Bcl-2 (ABIN3016826)

Bei, Xu, Lv, Yu, Xu, Che, Das, Tigges, Toxavidis, Ghiran, Shah, Li, Zhang, Das, Xiao: "Exercise-induced circulating extracellular vesicles protect against cardiac ischemia-reperfusion injury." dans: Basic research in cardiology, Vol. 112, Issue 4, pp. 38, (2018) (PubMed).

Li, Liu, Xie, Gu, Dai, Yao, Zhou: "Serum Exosomes Attenuate H2O2-Induced Apoptosis in Rat H9C2 Cardiomyocytes via ERK1/2." dans: Journal of cardiovascular translational research, (2018) (PubMed).

Détails sur Bcl-2

Antigène: Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Autre désignation: BCL2 (BCL2 Produits)

Synonymes: anticorps Bcl-2, anticorps PPP1R50, anticorps bcl-2, anticorps AW986256, anticorps C430015F12Rik, anticorps D630044D05Rik, anticorps D830018M01Rik, anticorps BCL-2, anticorps Bcl2, anticorps BCL2, apoptosis regulator, anticorps B cell leukemia/lymphoma 2, anticorps B-cell CLL/lymphoma 2a, anticorps B-cell CLL/lymphoma 2 protein, anticorps BCL2, anticorps Bcl2, anticorps bcl2a, anticorps BCL-2

Sujet: This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.,Bcl-2,PPP1R50,BCL2,Cancer,Tumor biomarkers,Invasion and Metastasis,Signal Transduction,PI3K-Akt Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Bcl 2 family,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,Autophagy,Death Receptor Signaling Pathway,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Immunology & Inflammation,Neuroscience,Neurodegenerative Diseases,Stem Cells,BCL2

Poids moléculaire: 22 kDa/26 kDa

ID gène: 596

UniProt: P10415

Pathways: Signalisation MAPK, Signalisation PI3K-Akt, Apoptose, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling