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CCR2 anticorps (AA 315-374)

CCR2 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3016845
  • Antigène Voir toutes CCR2 Anticorps
    CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
    Épitope
    • 16
    • 9
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 315-374
    Reactivité
    • 97
    • 47
    • 40
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 82
    • 14
    • 4
    • 1
    Lapin
    Clonalité
    • 77
    • 23
    • 1
    Polyclonal
    Conjugué
    • 41
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CCR2 est non-conjugé
    Application
    • 41
    • 26
    • 25
    • 15
    • 13
    • 12
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    LFHIALGCRI APLQKPVCGG PGVRPGKNVK VTTQGLLDGR GKGKSIGRAP EASLQDKEGA
     Réactivité croisée
    Humain, Souris
    Attributs du produit
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 315-374 of human CCR2 (NP_001116513.2).
    Isotype
    IgG
    Top Product
    Discover our top product CCR2 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Deci, Ferguson, Scatigno, Nguyen: "Modulating Macrophage Polarization through CCR2 Inhibition and Multivalent Engagement." dans: Molecular pharmaceutics, Vol. 15, Issue 7, pp. 2721-2731, (2018) (PubMed).

  • Antigène
    CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
    Autre désignation
    CCR2 (CCR2 Produits)
    Synonymes
    anticorps CC-CKR-2, anticorps CCR-2, anticorps CCR2A, anticorps CCR2B, anticorps CD192, anticorps CKR2, anticorps CKR2A, anticorps CKR2B, anticorps CMKBR2, anticorps MCP-1-R, anticorps ACKR5, anticorps CKRX, anticorps CRAM, anticorps CRAM-A, anticorps CRAM-B, anticorps HCR, anticorps Cc-ckr-2, anticorps Ccr2a, anticorps Ccr2b, anticorps Ckr2, anticorps Ckr2a, anticorps Ckr2b, anticorps Cmkbr2, anticorps mJe-r, anticorps C-C motif chemokine receptor 2, anticorps C-C motif chemokine receptor like 2, anticorps chemokine (C-C motif) receptor 2, anticorps CCR2, anticorps CCRL2, anticorps Ccr2, anticorps LOC484790
    Sujet
    This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.,CCR2,CC-CKR-2,CCR-2,CCR2A,CCR2B,CD192,CKR2,CKR2A,CKR2B,CMKBR2,MCP-1-R,FLJ78302,Cancer,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Immunology & Inflammation,CD markers,Cell Intrinsic Innate Immunity Signaling Pathway,Chemokines,Chemokine,Cardiovascular,CCR2
    Poids moléculaire
    41 kDa
    ID gène
    729230
    UniProt
    P41597
    Pathways
    cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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