NFAT1 anticorps

N° du produit ABIN3017385

Détail du produit anti-NFAT1 anticorps

Antigène: NFAT1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NFAT1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: A synthetic peptide of human NFATC2

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:1000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur NFAT1

Antigène: NFAT1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))

Autre désignation: NFATC2 (NFAT1 Produits)

Synonymes: anticorps NFATC2, anticorps AI607462, anticorps NF-ATc2, anticorps NFAT1, anticorps NFAT1-D, anticorps Nfatp, anticorps NFATP, anticorps nuclear factor of activated T-cells 2, anticorps nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2, anticorps NFATC2, anticorps nfatc2, anticorps Nfatc2

Sujet: This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized.,NFATC2,NFAT1,NFATP,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Signal Transduction,Endocrine & Metabolism,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,Cardiovascular,Hypoxia,Heart,Hypertrophy,NFATC2

Poids moléculaire: 76 kDa/97 kDa/98 kDa/99 kDa/100 kDa

ID gène: 4773

UniProt: Q13469

Pathways: Signalisation RTK, Signalisation WNT, Fc-epsilon Receptor Signaling Pathway, VEGF Signaling, BCR Signaling