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CDKN1B anticorps (pThr187)
CDKN1B
Reactivité: Humain
WB, IHC
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN3020148
Détail du produit anti-CDKN1B anticorps
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Antigène
Voir toutes CDKN1B Anticorps
CDKN1B
(Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))
Épitope
Tous les épitopes à travers CDKN1B Anticorps.
pThr187
Reactivité
Toutes les réactivités sur CDKN1B Anticorps
Humain
Hôte
Toutes les hôtes sur CDKN1B Anticorps
Lapin
Clonalité
Toutes les clonalités sur CDKN1B Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers CDKN1B Anticorps
Cet anticorp CDKN1B est non-conjugé
Application
Tous les applications à travers CDKN1B Anticorps.
Western Blotting (WB), Immunohistochemistry (IHC)
Réactivité croisée
Humain
Attributs du produit
Phosphorylated Antibodies
Purification
Affinity purification
Immunogène
A phospho specific peptide corresponding to residues surrounding T187 of human CDKN1B/p27KIP1
Isotype
IgG
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Alternatives
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Information d'application
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Indications d'application
WB,1:500 - 1:1000,IHC,1:50 - 1:100
Restrictions
For Research Use only
Stockage
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Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Détails sur CDKN1B
(cache)
Antigène
CDKN1B
(Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))
Autre désignation
CDKN1B (CDKN1B Produits )
Synonymes
anticorps CDKN4, anticorps KIP1, anticorps MEN1B, anticorps MEN4, anticorps P27KIP1, anticorps cdkn1b, anticorps sb:cb611, anticorps wu:fb63g10, anticorps wu:fb64g10, anticorps wu:fe18e03, anticorps CDKN1B, anticorps Kip1, anticorps p27, anticorps FAM14D, anticorps ISG12, anticorps ISG12A, anticorps P27, anticorps Cdki1b, anticorps AA408329, anticorps AI843786, anticorps p27Kip1, anticorps cdkn1bl, anticorps cyclin dependent kinase inhibitor 1B, anticorps cyclin-dependent kinase inhibitor 1Bb, anticorps interferon alpha inducible protein 27, anticorps cyclin-dependent kinase inhibitor 1B, anticorps cyclin-dependent kinase inhibitor 1Ba, anticorps CDKN1B, anticorps cdkn1bb, anticorps IFI27, anticorps Cdkn1b, anticorps cdkn1ba
Sujet
This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4).,CDKN1B,CDKN4,KIP1,MEN1B,MEN4,P27KIP1,p27 KIP 1,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cancer,Signal Transduction,Kinase,Serine/threonine kinases,PI3K-Akt Signaling Pathway,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,G1/S Checkpoint,Immunology & Inflammation,Protein phosphorylation,CDKN1B
Poids moléculaire
22 kDa
ID gène
1027
UniProt
P46527
Pathways
Cycle Cellulaire , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Positive Regulation of Peptide Hormone Secretion , Negative Regulation of Hormone Secretion , Sensory Perception of Sound , Mitotic G1-G1/S Phases , DNA Replication , Positive Regulation of Endopeptidase Activity , Synthesis of DNA , Autophagy
Vus récemment
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