SNCA anticorps (pSer129)

N° du produit ABIN3020490

Détail du produit anti-SNCA anticorps

Antigène: SNCA (Synuclein, alpha (SNCA))

Épitope: pSer129

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNCA est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Phosphorylated Antibodies

Immunogène: A phospho specific peptide corresponding to residues surrounding S129 of human alpha-Synuclein

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SNCA

Antigène: SNCA (Synuclein, alpha (SNCA))

Autre désignation: SNCA (SNCA Produits)

Synonymes: anticorps snca, anticorps MGC64356, anticorps LOC619283, anticorps NACP, anticorps alphaSYN, anticorps PARK1, anticorps PARK4, anticorps PD1, anticorps synuclein alpha L homeolog, anticorps alpha-synuclein, anticorps synuclein alpha, anticorps synuclein, alpha, anticorps snca.L, anticorps LOC619283, anticorps SNCA, anticorps Snca

Sujet: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.,PD1,NACP,PARK1,PARK4,SNCA,Cell Biology & Developmental Biology,Apoptosis,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Dopamine Signaling in Parkinson's Disease,Neurodegenerative Diseases Markers,Protein phosphorylation,SNCA

Poids moléculaire: 11 kDa/13 kDa/14 kDa

ID gène: 6622

UniProt: P37840

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity