BMI1 anticorps (AA 120-326)
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- Antigène Voir toutes BMI1 Anticorps
- BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
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Épitope
- AA 120-326
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BMI1 est non-conjugé
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Application
- Western Blotting (WB), Immunoprecipitation (IP)
- Séquence
- EDKRIITDDE IISLSIEFFD QNRLDRKVNK DKEKSKEEVN DKRYLRCPAA MTVMHLRKFL RSKMDIPNTF QIDVMYEEEP LKDYYTLMDI AYIYTWRRNG PLPLKYRVRP TCKRMKISHQ RDGLTNAGEL ESDSGSDKAN SPAGGIPSTS SCLPSPSTPV QSPHPQFPHI SSTMNGTSNS PSGNHQSSFA NRPRKSSVNG SSATSSG
- Réactivité croisée
- Humain, Souris, Rat
- Attributs du produit
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 120-326 of human Bmi1 (NP_005171.4).
- Isotype
- IgG
- Top Product
- Discover our top product BMI1 Anticorps primaire
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- Indications d'application
- WB,1:500 - 1:2000,IP,1:50 - 1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid freeze / thaw cycles
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
- Autre désignation
- BMI1 (BMI1 Produits)
- Sujet
- This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene.,BMI1,FLVI2/BMI1,PCGF4,RNF51,flvi-2/bmi-1,Bmi1,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,G1/S Checkpoint,BMI1
- Poids moléculaire
- 36 kDa
- ID gène
- 648
- UniProt
- P35226
- Pathways
- Cycle Cellulaire, Autophagy
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