Caspase 3 anticorps (AA 100-200)

N° du produit ABIN3020698

Détail du produit anti-Caspase 3 anticorps

Antigène: Caspase 3 (CASP3)

Épitope: AA 100-200

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caspase 3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: MRDVSKEDHS KRSSFVCVLL SHGEEGIIFG TNGPVDLKKI TNFFRGDRCR SLTGKPKLFI IQACRGTELD CGIETDSGVD DDMACHKIPV EADFLYAYST A

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human Caspase-3 (NP_004337.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-Caspase 3 (ABIN3020698)

Jiang, Liao, He, Xin, Tu, Kong, Cui, Wang, Quan, Li, Zhang, Wang: "FoxM1 Directs STAT3 Expression Essential for Human Endometrial Stromal Decidualization." dans: Scientific reports, Vol. 5, pp. 13735, (2016) (PubMed).

Wang, Tan, Mao, Lei, Wang, Hu, Chen, She, Zhu, Wang: "The marine metabolite SZ-685C induces apoptosis in primary human nonfunctioning pituitary adenoma cells by inhibition of the Akt pathway in vitro." dans: Marine drugs, Vol. 13, Issue 3, pp. 1569-80, (2016) (PubMed).

Wang, Li, Chen, Tan, Sun, Xia, Li, Yu, Gong, Tang, Ji, Yuan, Shanglong Yao, Shang: "Maresin 1 Inhibits Epithelial-to-Mesenchymal Transition in Vitro and Attenuates Bleomycin Induced Lung Fibrosis in Vivo." dans: Shock (Augusta, Ga.), Vol. 44, Issue 5, pp. 496-502, (2016) (PubMed).

Li, Yuan, Yang, Cao, Zhou, Xie, Tu, Zhang, Wang: "Immunoliposome co-delivery of bufalin and anti-CD40 antibody adjuvant induces synergetic therapeutic efficacy against melanoma." dans: International journal of nanomedicine, Vol. 9, pp. 5683-700, (2015) (PubMed).

Wu, Guo, Hui, Ye, Xiang, Wan, Zou, Ma, Sun, Yang, Guo: "Stanniocalcin-1 protects bovine intestinal epithelial cells from oxidative stress-induced damage." dans: Journal of veterinary science, Vol. 15, Issue 4, pp. 475-83, (2015) (PubMed).

Ye, Jiang, Cui, Zhu, Sun, Wang, Zohaib, Dong, Ruan, Song, He, Chen, Cao: "Etanercept reduces neuroinflammation and lethality in mouse model of Japanese encephalitis." dans: The Journal of infectious diseases, Vol. 210, Issue 6, pp. 875-89, (2014) (PubMed).

Qiu, Zhou, Jin, Yu, Liu, Liu, Qin, Xie, Zhu: "In vitro antioxidant and antiproliferative effects of ellagic acid and its colonic metabolite, urolithins, on human bladder cancer T24 cells." dans: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 59, pp. 428-37, (2014) (PubMed).

Détails sur Caspase 3

Antigène: Caspase 3 (CASP3)

Autre désignation: CASP3 (CASP3 Produits)

Synonymes: anticorps CPP32, anticorps CPP32B, anticorps SCA-1, anticorps A830040C14Rik, anticorps AC-3, anticorps Apopain, anticorps CC3, anticorps Caspase-3, anticorps Lice, anticorps Yama, anticorps mldy, anticorps xcpp32, anticorps casp3, anticorps zgc:100890, anticorps CASP-3, anticorps caspase-3, anticorps caspase 3, anticorps caspase 3 S homeolog, anticorps caspase 3, apoptosis-related cysteine peptidase a, anticorps caspase 3, apoptosis-related cysteine peptidase, anticorps CASP3, anticorps Casp3, anticorps casp3.S, anticorps casp3a

Sujet: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.,CPP32,CPP32B,SCA-1,Active Caspase 3,CASP3,active Caspase-3,Caspase 3,Caspase-3 p12,caspase-3,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Caspases,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,Death Receptor Signaling Pathway,Hippo Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,CASP3

Poids moléculaire: 31 kDa

ID gène: 836

UniProt: P42574

Pathways: Apoptose, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation