NEFL anticorps (AA 400-543)

N° du produit ABIN3020809

Détail du produit anti-NEFL anticorps

Antigène: NEFL (Neurofilament, Light Polypeptide (NEFL))

Épitope: AA 400-543

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NEFL est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: LSFTSVGSIT SGYSQSSQVF GRSAYGGLQT SSYLMSTRSF PSYYTSHVQE EQIEVEETIE AAKAEEAKDE PPSEGEAEEE EKDKEEAEEE EAAEEEEAAK EESEEAKEEE EGGEGEEGEE TKEAEEEEKK VEGAGEEQAA KKKD

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 400-543 of human Neurofilament L (NP_006149.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur NEFL

Antigène: NEFL (Neurofilament, Light Polypeptide (NEFL))

Autre désignation: NEFL (NEFL Produits)

Synonymes: anticorps NEFL, anticorps nefl, anticorps zgc:136626, anticorps AI847934, anticorps CMT2E, anticorps NF-L, anticorps NF68, anticorps Nfl, anticorps CMT1F, anticorps NFL, anticorps XNF-L, anticorps neurofilament light, anticorps neurofilament, light polypeptide, anticorps neurofilament, light polypeptide b, anticorps neurofilament, light L homeolog, anticorps NEFL, anticorps neflb, anticorps Nefl, anticorps nefl.L

Sujet: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.,NEFL,CMT1F,CMT2E,NF-L,NF68,NFL,PPP1R110,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Intermediate Filaments,Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Stem Cells,Neural Stem Cell marker,Neuron marker,Axon marker,NEFL

Poids moléculaire: 61 kDa

ID gène: 4747

UniProt: P07196